Intestinal barrier in human health and disease
N Di Tommaso, A Gasbarrini, FR Ponziani - International journal of …, 2021 - mdpi.com
The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …
protection from external factors. It consists of epithelial cells, immune cells and their …
[HTML][HTML] Chronic inflammation in the etiology of disease across the life span
Although intermittent increases in inflammation are critical for survival during physical injury
and infection, recent research has revealed that certain social, environmental and lifestyle …
and infection, recent research has revealed that certain social, environmental and lifestyle …
Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome
Objective The microbiome directly affects the balance of pro-inflammatory and anti-
inflammatory responses in the gut. As microbes thrive on dietary substrates, the question …
inflammatory responses in the gut. As microbes thrive on dietary substrates, the question …
Role of metabolic endotoxemia in systemic inflammation and potential interventions
S Mohammad, C Thiemermann - Frontiers in immunology, 2021 - frontiersin.org
Diet-induced metabolic endotoxemia is an important factor in the development of many
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …
Smoking, alcohol consumption, and 24 gastrointestinal diseases: Mendelian randomization analysis
Background: Whether the positive associations of smoking and alcohol consumption with
gastrointestinal diseases are causal is uncertain. We conducted this Mendelian …
gastrointestinal diseases are causal is uncertain. We conducted this Mendelian …
Host-microbiome interactions: Gut-Liver axis and its connection with other organs
An understanding of connections between gut microbiome and liver has provided important
insights into the pathophysiology of liver diseases. Since gut microbial dysbiosis increases …
insights into the pathophysiology of liver diseases. Since gut microbial dysbiosis increases …
Alcohol's Impact on the Gut and Liver
K Pohl, P Moodley, AD Dhanda - Nutrients, 2021 - mdpi.com
Alcohol is inextricably linked with the digestive system. It is absorbed through the gut and
metabolised by hepatocytes within the liver. Excessive alcohol use results in alterations to …
metabolised by hepatocytes within the liver. Excessive alcohol use results in alterations to …
Alcohol-associated tissue injury: current views on pathophysiological mechanisms
L Simon, FM Souza-Smith… - Annual review of …, 2022 - annualreviews.org
At-risk alcohol use is a major contributor to the global health care burden and leads to
preventable deaths and diseases including alcohol addiction, alcoholic liver disease …
preventable deaths and diseases including alcohol addiction, alcoholic liver disease …
Colorectal cancer and alcohol consumption—populations to molecules
M Rossi, M Jahanzaib Anwar, A Usman… - Cancers, 2018 - mdpi.com
Colorectal cancer (CRC) is a major cause of morbidity and mortality, being the third most
common cancer diagnosed in both men and women in the world. Several environmental …
common cancer diagnosed in both men and women in the world. Several environmental …
Leaky gut and autoimmunity: An intricate balance in individuals health and the diseased state
Damage to the tissue and the ruining of functions characterize autoimmune syndromes. This
review centers around leaky gut syndromes and how they stimulate autoimmune …
review centers around leaky gut syndromes and how they stimulate autoimmune …