Structure and function of the ependymal barrier and diseases associated with ependyma disruption

AJ Jiménez, MD Domínguez-Pinos, MM Guerra… - Tissue …, 2014 - Taylor & Francis
The neuroepithelium is a germinal epithelium containing progenitor cells that produce
almost all of the central nervous system cells, including the ependyma. The neuroepithelium …

[HTML][HTML] Harnessing cerebrospinal fluid circulation for drug delivery to brain tissues

GN Kouzehgarani, T Feldsien, HH Engelhard… - Advanced Drug Delivery …, 2021 - Elsevier
Initially thought to be useful only to reach tissues in the immediate vicinity of the CSF
circulatory system, CSF circulation is now increasingly viewed as a viable pathway to deliver …

Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters

SD Lolansen, N Rostgaard, D Barbuskaite… - Fluids and barriers of the …, 2022 - Springer
Introduction Posthemorrhagic hydrocephalus (PHH) often develops following hemorrhagic
events such as intraventricular hemorrhage (IVH) and subarachnoid hemorrhage (SAH) …

Riding the wave of ependymal cilia: genetic susceptibility to hydrocephalus in primary ciliary dyskinesia

L Lee - Journal of neuroscience research, 2013 - Wiley Online Library
Congenital hydrocephalus is a relatively common and debilitating birth defect with several
known physiological causes. Dysfunction of motile cilia on the ependymal cells that line the …

Nonsurgical therapy for hydrocephalus: a comprehensive and critical review

MR Del Bigio, DL Di Curzio - Fluids and Barriers of the CNS, 2015 - Springer
Pharmacological interventions have been tested experimentally and clinically to prevent
hydrocephalus and avoid the need for shunting beginning in the 1950s. Clinical trials of …

Venous hemodynamics in neurological disorders: an analytical review with hydrodynamic analysis

CB Beggs - BMC medicine, 2013 - Springer
Venous abnormalities contribute to the pathophysiology of several neurological conditions.
This paper reviews the literature regarding venous abnormalities in multiple sclerosis (MS) …

Acquired hydrocephalus is associated with neuroinflammation, progenitor loss, and cellular changes in the subventricular zone and periventricular white matter

M Garcia-Bonilla, L Castaneyra-Ruiz, S Zwick… - Fluids and barriers of the …, 2022 - Springer
Background Hydrocephalus is a neurological disease with an incidence of 80–125 per
100,000 births in the United States. Neuropathology comprises ventriculomegaly …

Cerebrospinal fluid circulation and hydrocephalus

V Leinonen, R Vanninen, T Rauramaa - Handbook of clinical neurology, 2018 - Elsevier
Hydrocephalus (HC) is classically defined as dynamic imbalance between the production
and absorption of cerebrospinal fluid (CSF) leading to enlarged ventricles. Potential …

Neuroimaging in pediatric hydrocephalus

P Krishnan, C Raybaud, S Palasamudram… - The Indian Journal of …, 2019 - Springer
The objective of this review is to discuss the role of neuroimaging in evaluating pediatric and
fetal hydrocephalus based on possible pathophysiologic mechanisms and in the context of …

CSF hypersecretion versus impaired CSF absorption in posthemorrhagic hydrocephalus: a systematic review

SD Ben-Shoshan, SD Lolansen, TI Mathiesen… - Acta …, 2023 - Springer
Background The molecular mechanisms underlying development of posthemorrhagic
hydrocephalus (PHH) remain elusive. The aim of this systematic review was to evaluate …