Transfusion-related acute lung injury (TRALI) can occur during or after a transfusion, and
remains a leading cause of transfusion-associated morbidity and mortality. TRALI is caused …

COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …

Although platelets are the cellular mediators of thrombosis, they are also immune cells.
Platelets interact both directly and indirectly with immune cells, impacting their activation and …

Atherosclerosis is an underlying cause of a broad array of cardiovascular diseases
characterized by plaques, arterial wall thickening initiated by hyperlipidemia, pro …

Circulating platelets interact with leukocytes to modulate host immune and thrombotic
responses. In sepsis, platelet-leukocyte interactions are increased and have been …

Antibodies targeting human leukocyte antigen (HLA)/major histocompatibility complex
(MHC) proteins limit successful transplantation and transfusion, and their presence in blood …

BACKGROUND: While platelets have well-studied hemostatic functions, platelets are
immune cells that circulate at the interface between the vascular wall and white blood cells …

Background: Thrombocytopenia is common in preterm neonates. Platelet transfusions are
sometimes given to thrombocytopenic neonates with the hope of reducing the bleeding risk …

Platelets, key facilitators of primary hemostasis and thrombosis, have emerged as crucial
cellular mediators of innate immunity and inflammation. Exemplified by their ability to alter …

Platelets are small anucleate blood cells with a life span of 7 to 10 days. They are main
regulators of hemostasis. Balanced platelet activity is crucial to prevent bleeding or …