PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0): a report of the RANO group
Summary Response Assessment in Neuro-Oncology (RANO) response criteria have been
established and were updated in 2023 for MRI-based response evaluation of diffuse …
established and were updated in 2023 for MRI-based response evaluation of diffuse …
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
Microglial activation plays central roles in neuroinflammatory and neurodegenerative
diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein …
diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein …
Clinical applications of TSPO PET for glioma imaging: Current evidence and future perspective—A systematic review
Our aim was to provide a comprehensive overview of the existing literature concerning the
clinical applications of positron emission computed tomography (PET) with …
clinical applications of positron emission computed tomography (PET) with …
Translocator protein (18kDA)(TSPO) marks mesenchymal glioblastoma cell populations characterized by elevated numbers of tumor-associated macrophages
L Weidner, J Lorenz, S Quach, FK Braun… - Acta Neuropathologica …, 2023 - Springer
TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of
brain tumors. However, due to the heterogeneity of cell populations that contribute to the …
brain tumors. However, due to the heterogeneity of cell populations that contribute to the …
Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH–Wild-Type Glioblastoma
NL Albert, DV Nelwan, DF Fleischmann… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The 18-kDa translocator protein (TSPO) is gaining recognition as a relevant target in
glioblastoma imaging. However, data on the potential prognostic value of TSPO PET …
glioblastoma imaging. However, data on the potential prognostic value of TSPO PET …
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution
LM Bartos, SV Kirchleitner, ZI Kolabas, S Quach… - Science …, 2023 - science.org
Various cellular sources hamper interpretation of positron emission tomography (PET)
biomarkers in the tumor microenvironment (TME). We developed an approach of …
biomarkers in the tumor microenvironment (TME). We developed an approach of …
Multi-targeted neutron capture therapy combined with an 18 kDa translocator protein-targeted boron compound is an effective strategy in a rat brain tumor model
H Kashiwagi, Y Hattori, S Kawabata, R Kayama… - Cancers, 2023 - mdpi.com
Simple Summary In recent years, boron neutron capture therapy (BNCT) has attracted
attention as a treatment for high-grade gliomas, and clinical trials using an accelerator …
attention as a treatment for high-grade gliomas, and clinical trials using an accelerator …
[HTML][HTML] Machine learning-based approach reveals essential features for simplified TSPO PET quantification in ischemic stroke patients
A Zatcepin, A Kopczak, A Holzgreve, S Hein… - … für Medizinische Physik, 2024 - Elsevier
Introduction Neuroinflammation evaluation after acute ischemic stroke is a promising option
for selecting an appropriate post-stroke treatment strategy. To assess neuroinflammation in …
for selecting an appropriate post-stroke treatment strategy. To assess neuroinflammation in …
Clinical Theranostics in Recurrent Gliomas: A Review
AR Hoggarth, S Muthukumar, SM Thomas, J Crowley… - Cancers, 2024 - mdpi.com
Simple Summary This paper discusses the challenges in treating high-grade gliomas,
particularly glioblastomas, which are aggressive brain tumors with high recurrence rates. It …
particularly glioblastomas, which are aggressive brain tumors with high recurrence rates. It …
Enhancing predictability of IDH mutation status in glioma patients at initial diagnosis: a comparative analysis of radiomics from MRI, [18F]FET PET, and TSPO PET
Abstract Purpose According to the World Health Organization classification for tumors of the
central nervous system, mutation status of the isocitrate dehydrogenase (IDH) genes has …
central nervous system, mutation status of the isocitrate dehydrogenase (IDH) genes has …