Classical and novel approaches to the preclinical testing of anxiolytics: a critical evaluation

J Haller, M Aliczki, KG Pelczer - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Over 80% of current anxiety studies employ one of the tests that were developed earlier
than, or concurrently with the elevated plus-maze, ie before 1985. Considering 1985 as a …

Multiple nonauditory cortical regions innervate the auditory midbrain

BMJ Olthof, A Rees, SE Gartside - Journal of Neuroscience, 2019 - Soc Neuroscience
Our perceptual experience of sound depends on the integration of multiple sensory and
cognitive domains, however the networks subserving this integration are unclear …

The distribution of fos immunoreactivity in rat brain following freezing and escape responses elicited by electrical stimulation of the inferior colliculus

MR Lamprea, FP Cardenas, DM Vianna, VM Castilho… - Brain research, 2002 - Elsevier
Several sources of evidence indicate that the inferior colliculus also integrates acoustic
information of an aversive nature besides its well-known role as a relay station for auditory …

Brainstem correlates of defensive states in humans

JMP Baas, J Milstein, M Donlevy, C Grillon - Biological psychiatry, 2006 - Elsevier
BACKGROUND: Brainstem auditory evoked potentials (BAEP) reflect the activation of
brainstem nuclei in the first milliseconds after presentation of an auditory stimulus. These …

Neuroanatomical and psychopharmacological evidence for interaction between opioid and GABAergic neural pathways in the modulation of fear and defense elicited …

GCD Eichenberger, SJ Ribeiro, MY Osaki… - …, 2002 - Elsevier
The effects of central administration of opioid antagonists on the aversive responses elicited
by electrical (at the freezing and escape thresholds) or chemical stimulation (crossings …

Topographic and functional neuroanatomical study of GABAergic disinhibitory striatum–nigral inputs and inhibitory nigrocollicular pathways: Neural hodology …

L Castellan-Baldan, M da Costa Kawasaki… - Journal of Chemical …, 2006 - Elsevier
Considering the influence of the substantia nigra on mesencephalic neurons involved with
fear-induced reactions organized in rostral aspects of the dorsal midbrain, the present work …

Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships

RO Beleboni, ROG Carolino, AB Pizzo… - Cellular and molecular …, 2004 - Springer
The GABAergic neurotransmission has been implicated in the modulation of many neural
networks in forebrain, midbrain and hindbrain, as well as, in several neurological disorders …

5-HT2-and D1-mechanisms of the basolateral nucleus of the amygdala enhance conditioned fear and impair unconditioned fear

CE Macedo, RCR Martinez, L Albrechet-Souza… - Behavioural Brain …, 2007 - Elsevier
The inferior colliculus (IC) is involved in processing of auditory information, but also
integrates acoustic information of aversive nature. In fact, chemical stimulation of the IC with …

Glutamatergic neurotransmission mediated by NMDA receptors in the inferior colliculus can modulate haloperidol-induced catalepsy

LL Melo, P Santos, P Medeiros, RO Mello, EAM Ferrari… - Brain research, 2010 - Elsevier
The inferior colliculus (IC) is primarily involved in the processing of auditory information, but
it is distinguished from other auditory nuclei in the brainstem by its connections with …

Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of μ1-and κ-opioid receptor blockade on escape behavior …

MY Osaki, L Castellan-Baldan, F Calvo, AD Carvalho… - Brain research, 2003 - Elsevier
Deep layers of the superior colliculus (DLSC), the dorsal and ventral periaqueductal gray
matter (PAG), and inferior colliculus (IC) are midbrain structures involved in the generation of …