Dopamine D2-Like Receptors Modulate Unconditioned Fear: Role of the Inferior Colliculus

AR de Oliveira, AC Colombo, S Muthuraju… - PLoS …, 2014 - journals.plos.org
Background A reduction of dopamine release or D2 receptor blockade in the terminal fields
of the mesolimbic system clearly reduces conditioned fear. Injections of haloperidol, a …

[HTML][HTML] Dual role of dopamine D2-like receptors in the mediation of conditioned and unconditioned fear

ML Brandão, AR de Oliveira, S Muthuraju, AC Colombo… - FEBS letters, 2015 - Elsevier
A reduction of dopamine release or D 2 receptor blockade in the terminal fields of the
mesolimbic system, particularly the amygdala, clearly reduces conditioned fear. Similar D 2 …

Behavioral inhibition as a risk factor for psychopathology.

J Kagan - 2008 - psycnet.apa.org
Investigators who believed in the importance of biological processes recognized that alcohol
dependents, criminals, depressives, and agoraphobics did not possess their maladaptive …

Distribution of Fos immunoreactivity in the rat brain after freezing or escape elicited by inhibition of glutamic acid decarboxylase or antagonism of GABA-A receptors in …

KG Borelli, C Ferreira-Netto, ML Brandão - Behavioural brain research, 2006 - Elsevier
It has been shown that electrical stimulation of the central nucleus of the inferior colliculus
(IC) at freezing or escape thresholds activates different neural circuits in the brain. Since …

Isolation-induced changes in ultrasonic vocalization, fear-potentiated startle and prepulse inhibition in rats

ML Nunes Mamede Rosa, MJ Nobre… - …, 2005 - karger.com
Isolation causes important changes in the behavioral reactivity of rats to environmental
stimuli. These changes include deficit in sensorimotor gating and altered fear-like responses …

D2-like receptor activation by intranasal dopamine attenuates fear responses induced by electrical stimulation of the dorsal periaqueductal grey matter, but fails to …

RM de Figueiredo… - Journal of …, 2022 - journals.sagepub.com
Background: Panic-like reactions elicited by electrical stimulation of the dorsal
periaqueductal grey matter (ES-dPAG) seem to be regulated by dopamine (DA). We showed …

Enhancement of acoustic evoked potentials and impairment of startle reflex induced by reduction of GABAergic control of the neural substrates of aversion in the …

MJ Nobre, G Sandner, ML Brandão - Hearing research, 2003 - Elsevier
The neural network of the inferior colliculus (IC), implicated in the generation of defensive
behavior to aversive acoustic stimuli, is under tonic GABAergic control. Dopamine also …

Tone-specific and nonspecific plasticity of inferior colliculus elicited by pseudo-conditioning: role of acetylcholine and auditory and somatosensory cortices

W Ji, N Suga - Journal of neurophysiology, 2009 - journals.physiology.org
Experience-dependent plasticity in the central sensory systems depends on activation of
both the sensory and neuromodulatory systems. Sensitization or nonspecific augmentation …

Distinct Fos expression in the brain following freezing behavior elicited by stimulation with NMDA of the ventral or dorsal inferior colliculus

C Ferreira-Netto, KG Borelli, ML Brandão - Experimental neurology, 2007 - Elsevier
The inferior colliculus (IC) is an important relay station for ascending auditory information to
the medial geniculate nucleus (MGN) and temporal cortex. It has been reported that the …

Distinct effects of haloperidol in the mediation of conditioned fear in the mesolimbic system and processing of unconditioned aversive information in the inferior …

S Muthuraju, MJ Nobre, VMN Saito, ML Brandao - Neuroscience, 2014 - Elsevier
Chemical and electrical stimulation of the inferior colliculus (IC) causes defensive behavior.
Electrical stimulation of the IC at the escape threshold enhances dopamine (DA) release in …