[HTML][HTML] Protein-protein interaction network of celiac disease

MZ Azodi, H Peyvandi, M Rostami-Nejad… - … and Hepatology from …, 2016 - ncbi.nlm.nih.gov
Aim: The aim of this study is to investigate the Protein-Protein Interaction Network of Celiac
Disease. Background: Celiac disease (CD) is an autoimmune disease with susceptibility of …

Epigenetic profiling of human brain differential DNA methylation networks in schizophrenia

SA Lee, KC Huang - BMC medical genomics, 2016 - Springer
Background Epigenetics of schizophrenia provides important information on how the
environmental factors affect the genetic architecture of the disease. DNA methylation plays a …

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

J Fernández-Tajes, KJ Gaulton, M van de Bunt… - Genome Medicine, 2019 - Springer
Background Genome-wide association studies (GWAS) have identified several hundred
susceptibility loci for type 2 diabetes (T2D). One critical, but unresolved, issue concerns the …

Bipolar disorder in youth is associated with increased levels of vitamin D-binding protein

B Petrov, A Aldoori, C James, K Yang… - Translational …, 2018 - nature.com
Genetic, dietary, and inflammatory factors contribute to the etiology of major mood disorders
(MMD), thus impeding the identification of specific biomarkers to assist in diagnosis and …

Switching the clientele

S Sucic, F Koban, A El-Kasaby, O Kudlacek… - Journal of Biological …, 2013 - ASBMB
The serotonin transporter (SERT) maintains serotonergic neurotransmission via rapid
reuptake of serotonin from the synaptic cleft. SERT relies exclusively on the coat protein …

Construction and analysis of protein-protein interaction networks based on proteomics data of prostate cancer

C Chen, H Shen, LG Zhang, J Liu… - International …, 2016 - spandidos-publications.com
Currently, using human prostate cancer (PCa) tissue samples to conduct proteomics
research has generated a large amount of data; however, only a very small amount has …

Epigenetics in schizophrenia: a pilot study of global DNA methylation in different brain regions associated with higher cognitive functions

R Alelú-Paz, FJ Carmona, JV Sanchez-Mut… - Frontiers in …, 2016 - frontiersin.org
Attempts to discover genes that are involved in the pathogenesis of major psychiatric
disorders have been frustrating and often fruitless. Concern is building about the need to …

Increased autocrine interleukin‐6 production is significantly associated with worse clinical outcome in patients with chronic lymphocytic leukemia

HQ Wang, L Jia, YT Li, T Farren… - Journal of cellular …, 2019 - Wiley Online Library
Chronic lymphocytic leukemia (CLL) remains incurable with current standard therapy. We
have previously reported that an increased expression of interleukin‐6 (IL‐6) receptor …

Upregulation of S100A8 in peripheral blood mononuclear cells from patients with depression treated with SSRIs: a pilot study

C Gamboa-Sánchez, E Becerril-Villanueva… - Proteome Science, 2023 - Springer
Background Major depressive disorder (MDD) affects more than 350 million people
worldwide, and there is currently no laboratory test to diagnose it. This pilot study aimed to …

Systems approach to identify common genes and pathways associated with response to selective serotonin reuptake inhibitors and major depression risk

A Srivastava, P Singh, H Gupta, H Kaur… - International journal of …, 2019 - mdpi.com
Despite numerous studies on major depressive disorder (MDD) susceptibility, the precise
underlying molecular mechanism has not been elucidated which restricts the development …