Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Transplanting neural progenitor cells to restore connectivity after spinal cord injury

I Fischer, JN Dulin, MA Lane - Nature Reviews Neuroscience, 2020 - nature.com
Spinal cord injury remains a scientific and therapeutic challenge with great cost to
individuals and society. The goal of research in this field is to find a means of restoring lost …

Biomimetic 3D-printed scaffolds for spinal cord injury repair

J Koffler, W Zhu, X Qu, O Platoshyn, JN Dulin, J Brock… - Nature medicine, 2019 - nature.com
Current methods for bioprinting functional tissue lack appropriate biofabrication techniques
to build complex 3D microarchitectures essential for guiding cell growth and promoting …

Neural stem cell-derived small extracellular vesicles attenuate apoptosis and neuroinflammation after traumatic spinal cord injury by activating autophagy

Y Rong, W Liu, J Wang, J Fan, Y Luo, L Li, F Kong… - Cell death & …, 2019 - nature.com
Spinal cord injury (SCI) can cause severe irreversible motor dysfunction and even death.
Neural stem cell (NSC) transplantation can promote functional recovery after acute SCI in …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Applications of chitosan-based biomaterials: From preparation to spinal cord injury neuroprosthetic treatment

W Xiang, H Cao, H Tao, L Jin, Y Luo, F Tao… - International Journal of …, 2023 - Elsevier
Spinal cord injury (SCI)-related disabilities are a serious problem in the modern society.
Further, the treatment of SCI is highly challenging and is urgently required in clinical …

3D bioprinting of neural tissues

M Cadena, L Ning, A King, B Hwang… - Advanced …, 2021 - Wiley Online Library
The human nervous system is a remarkably complex physiological network that is inherently
challenging to study because of obstacles to acquiring primary samples. Animal models …

Neural stem cell delivery via porous collagen scaffolds promotes neuronal differentiation and locomotion recovery in spinal cord injury

A Kourgiantaki, DS Tzeranis, K Karali… - NPJ Regenerative …, 2020 - nature.com
Neural stem cell (NSC) grafts have demonstrated significant effects in animal models of
spinal cord injury (SCI), yet their clinical translation remains challenging. Significant …

The roles and applications of neural stem cells in spinal cord injury repair

W Guo, X Zhang, J Zhai, J Xue - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Spinal cord injury (SCI), which has no current cure, places a severe burden on patients.
Stem cell-based therapies are considered promising in attempts to repair injured spinal …

[HTML][HTML] Advanced approaches to regenerate spinal cord injury: the development of cell and tissue engineering therapy and combinational treatments

J Saremi, N Mahmoodi, M Rasouli, FE Ranjbar… - Biomedicine & …, 2022 - Elsevier
Spinal cord injury (SCI) is a central nervous system (CNS) devastate event that is commonly
caused by traumatic or non-traumatic events. The reinnervation of spinal cord axons is …