Trial watch: chemotherapy-induced immunogenic cell death in oncology
Immunogenic cell death (ICD) refers to an immunologically distinct process of regulated cell
death that activates, rather than suppresses, innate and adaptive immune responses. Such …
death that activates, rather than suppresses, innate and adaptive immune responses. Such …
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity
Most metastatic cancers remain incurable due to the emergence of apoptosis-resistant
clones, fuelled by intratumour heterogeneity and tumour evolution. To improve treatment …
clones, fuelled by intratumour heterogeneity and tumour evolution. To improve treatment …
Exploring nanocarriers as innovative materials for advanced drug delivery strategies in onco-immunotherapies
P Tiwari, RP Shukla, K Yadav, D Panwar… - Journal of Molecular …, 2024 - Elsevier
In recent years, Onco-immunotherapies (OIMTs) have been shown to be a potential therapy
option for cancer. Several immunotherapies have received regulatory approval, while many …
option for cancer. Several immunotherapies have received regulatory approval, while many …
The mechanism and clinical application of DNA damage repair inhibitors combined with immune checkpoint inhibitors in the treatment of urologic cancer
D Xie, B Jiang, S Wang, Q Wang, G Wu - Frontiers in Cell and …, 2023 - frontiersin.org
Urologic cancers such as kidney, bladder, prostate, and uroepithelial cancers have recently
become a considerable global health burden, and the response to immunotherapy is limited …
become a considerable global health burden, and the response to immunotherapy is limited …
Extracellular vesicles-powered immunotherapy: Unleashing the potential for safer and more effective cancer treatment
Cancer treatment has seen significant advancements with the introduction of Onco-
immunotherapies (OIMTs). Although some of these therapies have received approval for …
immunotherapies (OIMTs). Although some of these therapies have received approval for …
Tumor cell membrane‐based vaccines: a potential boost for cancer immunotherapy
M Yang, J Zhou, L Lu, D Deng, J Huang, Z Tang… - …, 2024 - Wiley Online Library
Because therapeutic cancer vaccines can, in theory, eliminate tumor cells specifically with
relatively low toxicity, they have long been considered for application in repressing cancer …
relatively low toxicity, they have long been considered for application in repressing cancer …
Label-Free Multiplex Profiling of Exosomal Proteins with a Deep Learning-Driven 3D Surround-Enhancing SERS Platform for Early Cancer Diagnosis
M Chen, H Wang, Y Zhang, H Jiang, T Li, L Liu… - Analytical …, 2024 - ACS Publications
Identification of protein profiling on plasma exosomes by SERS can be a promising strategy
for early cancer diagnosis. However, it is still challenging to detect multiple exosomal …
for early cancer diagnosis. However, it is still challenging to detect multiple exosomal …
The one-two punch: TIM-3 blockade targets immune and tumor cells to knock out pediatric brain tumors
J Lee, JD Lathia - Cancer Cell, 2023 - cell.com
Diffuse midline gliomas (DMGs) pose treatment challenges due to their location within the
brainstem and invasive nature. Although classical immune checkpoint inhibitors have …
brainstem and invasive nature. Although classical immune checkpoint inhibitors have …
Exploiting cell death and tumor immunity in cancer therapy: challenges and future directions
J Lu, R He, Y Liu, J Zhang, H Xu, T Zhang… - Frontiers in Cell and …, 2024 - frontiersin.org
Cancer remains a significant global challenge, with escalating incidence rates and a
substantial burden on healthcare systems worldwide. Herein, we present an in-depth …
substantial burden on healthcare systems worldwide. Herein, we present an in-depth …
Promotion of ICD via Nanotechnology
Y Qin, H Zhang, Y Li, T Xie, S Yan… - Macromolecular …, 2023 - Wiley Online Library
Immunotherapy represents the most promising treatment strategy for cancer, but suffers from
compromised therapeutic efficiency due to low immune activity of tumor cells and an …
compromised therapeutic efficiency due to low immune activity of tumor cells and an …