The use of peptide antigens for vaccination, compared with traditional vaccines, has
advantages such as purity and low risk of adverse effects and disadvantages such as weak …

CD4+ T cells have been found to play critical roles in the control of both acute and chronic
Toxoplasma infection. Previous studies identified a protective role for the Toxoplasma CD4+ …

Introduction: Recently, subunit vaccines are replacing some of the traditional vaccines
because they offer a higher margin of safety. However, generally subunit vaccines have low …

Chitosan, a biopolymer, has versatile physicochemical and biological/pharmacological
properties which are treasury for the pharmaceutical field. However, the shortcomings of …

Subunit vaccines are one of the major focuses of modern vaccine development. They tend to
be more tolerable than whole organism vaccines, however, they also tend to be less …

The immune system has evolved to recognize and eliminate pathogens; this recognition
relies on the identification of structural molecular patterns within unique tissue …

Self-assembly has become a useful way of constructing biomaterials for a variety of
applications ranging from cell culture to tissue engineering. Attractive features of self …

In this proof-of-concept study we report the use of< 15nm, water soluble, inorganic
nanoparticles as a vaccine delivery system for a blood stage malaria vaccine. The …

Developing a novel class of vaccine is pivotal for eliminating and eradicating malaria.
Preceding investigations demonstrated partial blocking activity in malaria transmission …

Coiled coils represent the most frequent protein oligomerization motif in nature and are
involved in many important biological processes. The prototype interhelical ionic interaction …