[HTML][HTML] A self-adjuvanted nanoparticle based vaccine against infectious bronchitis virus
Infectious bronchitis virus (IBV) affects poultry respiratory, renal and reproductive systems.
Currently the efficacy of available live attenuated or killed vaccines against IBV has been …
Currently the efficacy of available live attenuated or killed vaccines against IBV has been …
[HTML][HTML] Engineering and characterization of a novel Self Assembling Protein for Toxoplasma peptide vaccine in HLA-A*11:01, HLA-A*02:01 and HLA-B*07:02 …
K El Bissati, Y Zhou, SM Paulillo, SK Raman… - Scientific Reports, 2020 - nature.com
Fighting smart diseases requires smart vaccines. Novel ways to present protective
immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on …
immunogenic peptide epitopes to human immune systems are needed. Herein, we focus on …
[HTML][HTML] Design and optimization of peptide nanoparticles
TAPF Doll, R Dey, P Burkhard - Journal of nanobiotechnology, 2015 - Springer
Background Various supra-molecular structures form by self-assembly of proteins in a
symmetric fashion. Examples of such structures are viruses, some bacterial micro …
symmetric fashion. Examples of such structures are viruses, some bacterial micro …
[HTML][HTML] Design and development of a self-assembling protein nanoparticle displaying PfHAP2 antigenic determinants recognized by natural acquired antibodies
Backgrounds In order to move towards the elimination and eradication of malaria in the
world, the development of vaccines is inevitable. Many modern vaccines are based on …
world, the development of vaccines is inevitable. Many modern vaccines are based on …
Progress toward the clinical translation of bioinspired peptide and protein assemblies
KM Hainline, CN Fries, JH Collier - Advanced healthcare …, 2018 - Wiley Online Library
Supramolecular materials composed of proteins and peptides have been receiving
considerable attention toward a range of diseases and conditions from vaccines to drug …
considerable attention toward a range of diseases and conditions from vaccines to drug …
Engaging adaptive immunity with biomaterials
C Mora-Solano, JH Collier - Journal of Materials Chemistry B, 2014 - pubs.rsc.org
Adaptive immune responses, characterized by T cells and B cells engaging and responding
to specific antigens, can be raised by biomaterials containing proteins, peptides, and other …
to specific antigens, can be raised by biomaterials containing proteins, peptides, and other …
PD-1/PD-L1 参与肿瘤免疫逃逸的研究进展
吴介恒， 杨安钢， 温伟红 - 细胞与分子免疫学杂志, 2014 - cqvip.com
程序性死亡分子1 及其配体(PD-1/PD-L1) 是一对负性免疫共刺激分子, 正常情况下,
组织细胞表面的PD-L1 与淋巴细胞表面的PD-1 结合后, 可抑制淋巴细胞功能 …
组织细胞表面的PD-L1 与淋巴细胞表面的PD-1 结合后, 可抑制淋巴细胞功能 …
Design and characterization of a self-assembling protein nanoparticle displaying HIV-1 Env V1V2 loop in a native-like trimeric conformation as vaccine antigen
The RV144 HIV-1 clinical trial demonstrated modest vaccine efficacy and identified IgG
antibodies against the Env V1V2 loop that inversely correlated with risk of infection. Based …
antibodies against the Env V1V2 loop that inversely correlated with risk of infection. Based …
[HTML][HTML] Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle …
ME McCoy, HE Golden, TAPF Doll, Y Yang, SA Kaba… - Malaria journal, 2013 - Springer
Background A lack of defined correlates of immunity for malaria, combined with the inability
to induce long-lived sterile immune responses in a human host, demonstrate a need for …
to induce long-lived sterile immune responses in a human host, demonstrate a need for …
Harnessing supramolecular peptide nanotechnology in biomedical applications
The harnessing of peptides in biomedical applications is a recent hot topic. This arises
mainly from the general biocompatibility of peptides, as well as from the ease of tunability of …
mainly from the general biocompatibility of peptides, as well as from the ease of tunability of …