Transport phenomena in nanofluidics

RB Schoch, J Han, P Renaud - Reviews of modern physics, 2008 - APS
The transport of fluid in and around nanometer-sized objects with at least one characteristic
dimension below 100 nm enables the occurrence of phenomena that are impossible at …

Colloquium: Physical approaches to DNA sequencing and detection

M Zwolak, M Di Ventra - Reviews of Modern Physics, 2008 - APS
With the continued improvement of sequencing technologies, the prospect of genome-based
medicine is now at the forefront of scientific research. To realize this potential, however, a …

Speciation in mammals and the genetic species concept

RJ Baker, RD Bradley - Journal of mammalogy, 2006 - academic.oup.com
We define a genetic species as a group of genetically compatible interbreeding natural
populations that is genetically isolated from other such groups. This focus on genetic …

DNA sequencing: bench to bedside and beyond

CA Hutchison III - Nucleic acids research, 2007 - academic.oup.com
Fifteen years elapsed between the discovery of the double helix (1953) and the first DNA
sequencing (1968). Modern DNA sequencing began in 1977, with development of the …

Base-calling for next-generation sequencing platforms

C Ledergerber, C Dessimoz - Briefings in bioinformatics, 2011 - academic.oup.com
Next-generation sequencing platforms are dramatically reducing the cost of DNA
sequencing. With these technologies, bases are inferred from light intensity signals, a …

Fast DNA sequencing via transverse electronic transport

J Lagerqvist, M Zwolak, M Di Ventra - Nano letters, 2006 - ACS Publications
A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We
propose and theoretically show the feasibility of a protocol for sequencing based on the …

A new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesis

G Turcatti, A Romieu, M Fedurco… - Nucleic acids …, 2008 - academic.oup.com
Fluorescent 2′-deoxynucleotides containing a protecting group at the 3′-O-position are
reversible terminators enabling array-based DNA sequencing by synthesis (SBS) …

Genotyping technologies for genetic research

J Ragoussis - Annual review of genomics and human genetics, 2009 - annualreviews.org
The past few years have seen enormous advances in genotyping technology, including
chips that accommodate in excess of 1 million SNP assays. In addition, the cost per …

Methods and products for analyzing polymers

EY Chan - US Patent 8,168,380, 2012 - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …

Single-molecule DNA sequencing technologies for future genomics research

PK Gupta - Trends in biotechnology, 2008 - cell.com
During the current genomics revolution, the genomes of a large number of living organisms
have been fully sequenced. However, with the advent of new sequencing technologies …