Transport phenomena in nanofluidics
The transport of fluid in and around nanometer-sized objects with at least one characteristic
dimension below 100 nm enables the occurrence of phenomena that are impossible at …
dimension below 100 nm enables the occurrence of phenomena that are impossible at …
Colloquium: Physical approaches to DNA sequencing and detection
M Zwolak, M Di Ventra - Reviews of Modern Physics, 2008 - APS
With the continued improvement of sequencing technologies, the prospect of genome-based
medicine is now at the forefront of scientific research. To realize this potential, however, a …
medicine is now at the forefront of scientific research. To realize this potential, however, a …
Speciation in mammals and the genetic species concept
RJ Baker, RD Bradley - Journal of mammalogy, 2006 - academic.oup.com
We define a genetic species as a group of genetically compatible interbreeding natural
populations that is genetically isolated from other such groups. This focus on genetic …
populations that is genetically isolated from other such groups. This focus on genetic …
DNA sequencing: bench to bedside and beyond
CA Hutchison III - Nucleic acids research, 2007 - academic.oup.com
Fifteen years elapsed between the discovery of the double helix (1953) and the first DNA
sequencing (1968). Modern DNA sequencing began in 1977, with development of the …
sequencing (1968). Modern DNA sequencing began in 1977, with development of the …
Base-calling for next-generation sequencing platforms
C Ledergerber, C Dessimoz - Briefings in bioinformatics, 2011 - academic.oup.com
Next-generation sequencing platforms are dramatically reducing the cost of DNA
sequencing. With these technologies, bases are inferred from light intensity signals, a …
sequencing. With these technologies, bases are inferred from light intensity signals, a …
Fast DNA sequencing via transverse electronic transport
J Lagerqvist, M Zwolak, M Di Ventra - Nano letters, 2006 - ACS Publications
A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We
propose and theoretically show the feasibility of a protocol for sequencing based on the …
propose and theoretically show the feasibility of a protocol for sequencing based on the …
A new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesis
G Turcatti, A Romieu, M Fedurco… - Nucleic acids …, 2008 - academic.oup.com
Fluorescent 2′-deoxynucleotides containing a protecting group at the 3′-O-position are
reversible terminators enabling array-based DNA sequencing by synthesis (SBS) …
reversible terminators enabling array-based DNA sequencing by synthesis (SBS) …
Genotyping technologies for genetic research
J Ragoussis - Annual review of genomics and human genetics, 2009 - annualreviews.org
The past few years have seen enormous advances in genotyping technology, including
chips that accommodate in excess of 1 million SNP assays. In addition, the cost per …
chips that accommodate in excess of 1 million SNP assays. In addition, the cost per …
Methods and products for analyzing polymers
EY Chan - US Patent 8,168,380, 2012 - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …
US8168380B2 - Methods and products for analyzing polymers - Google Patents Methods and …
Single-molecule DNA sequencing technologies for future genomics research
PK Gupta - Trends in biotechnology, 2008 - cell.com
During the current genomics revolution, the genomes of a large number of living organisms
have been fully sequenced. However, with the advent of new sequencing technologies …
have been fully sequenced. However, with the advent of new sequencing technologies …