Natural products as a source of Alzheimer's drug leads
P Williams, A Sorribas, MJR Howes - Natural product reports, 2011 - pubs.rsc.org
Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …
The enzymes of β-lactam biosynthesis
Covering: up to May 2012The β-lactam antibiotics and related β-lactamase inhibitors are
amongst the most important small molecules in clinical use. Most, but not all, β-lactams …
amongst the most important small molecules in clinical use. Most, but not all, β-lactams …
Natural AChE inhibitors from plants and their contribution to Alzheimer's disease therapy
AP Murray, MB Faraoni, MJ Castro… - Current …, 2013 - ingentaconnect.com
As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in
Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE …
Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE …
[HTML][HTML] Cholinesterase inhibitors from botanicals
Alzheimer's disease (AD) is a progressive neurodegenerative disease, wherein a
progressive loss of cholinergic synapses occurs in hippocampus and neocortex. Decreased …
progressive loss of cholinergic synapses occurs in hippocampus and neocortex. Decreased …
[HTML][HTML] Chemistry and bioactivities of natural steroidal alkaloids
ML Xiang, BY Hu, ZH Qi, XN Wang, TZ Xie… - Natural Products and …, 2022 - Springer
Steroidal alkaloids possess the basic steroidal skeleton with a nitrogen atom in rings or side
chains incorporated as an integral part of the molecule. They have demonstrated a wide …
chains incorporated as an integral part of the molecule. They have demonstrated a wide …
Terpenoid‐alkaloids: their biosynthetic twist of fate and total synthesis
EC Cherney, PS Baran - Israel journal of chemistry, 2011 - Wiley Online Library
Terpenes and alkaloids are ever‐growing classes of natural products that provide new
molecular structures that inspire chemists and possess a broad range of biological activity …
molecular structures that inspire chemists and possess a broad range of biological activity …
Plant-derived acetylcholinesterase inhibitory alkaloids for the treatment of Alzheimer's disease
S Dall'Acqua - Botanics: Targets and Therapy, 2013 - Taylor & Francis
The inhibition of acetylcholinesterase (AChE) has been one of the most used strategies for
the treatment of Alzheimer's disease (AD). The AChE inhibitors (AChE-I) produce not only …
the treatment of Alzheimer's disease (AD). The AChE inhibitors (AChE-I) produce not only …
Alkaloids as drug leads in Alzheimer's treatment: Mechanistic and therapeutic insights
Alzheimer's disease (AD) has few effective treatment options and continues to be a major
global health concern. AD is a neurodegenerative disease that typically affects elderly …
global health concern. AD is a neurodegenerative disease that typically affects elderly …
Composition of alkaloids in different box tree varieties and their uptake by the box tree moth Cydalima perspectalis
Larvae of the moth Cydalima perspectalis are specialized on box trees (Buxus spp.). Native
to eastern Asia, the moth has been introduced to Europe in 2007 and is nowadays causing …
to eastern Asia, the moth has been introduced to Europe in 2007 and is nowadays causing …
Unexpected Presence of Graminan- and Levan-Type Fructans in the Evergreen Frost-Hardy Eudicot Pachysandra terminalis (Buxaceae): Purification, Cloning, and …
W Van den Ende, M Coopman, S Clerens… - Plant …, 2011 - academic.oup.com
About 15% of flowering plants accumulate fructans. Inulin-type fructans with β (2, 1) fructosyl
linkages typically accumulate in the core eudicot families (eg Asteraceae), while levan-type …
linkages typically accumulate in the core eudicot families (eg Asteraceae), while levan-type …