Alleviating symptoms in patients undergoing long-term hemodialysis: a focus on chronic kidney disease-associated pruritus

R Agarwal, J Burton, M Gallieni… - Clinical kidney …, 2023 - academic.oup.com
Since the breakthrough of kidney replacement therapy, increases in life expectancy for
patients with end-stage kidney disease have been limited. However, patients have become …

[HTML][HTML] Novel approach to unpleasant symptom clusters surrounding pruritus in patients with chronic kidney disease and on dialysis therapy

RS Ahdoot, K Kalantar-Zadeh, JO Burton… - Current opinion in …, 2022 - journals.lww.com
Novel approach to unpleasant symptom clusters surrounding pr... : Current Opinion in
Nephrology and Hypertension Novel approach to unpleasant symptom clusters surrounding …

[HTML][HTML] Efficacy of difelikefalin for the treatment of moderate to severe pruritus in hemodialysis patients: pooled analysis of KALM-1 and KALM-2 phase 3 studies

J Topf, T Wooldridge, K McCafferty, M Schömig… - Kidney medicine, 2022 - Elsevier
Rationale & Objective Chronic kidney disease–associated pruritus (CKD-aP) in patients
treated by hemodialysis (HD) impairs quality of life (QoL). Difelikefalin, a selective κ-opioid …

Itching in dialysis patients: impact on health-related quality of life and interactions with sleep problems and psychological symptoms—results from the RENINE/PROMs …

EM van der Willik, R Lengton… - Nephrology Dialysis …, 2022 - academic.oup.com
Background Itching (pruritus) is common in dialysis patients, but little is known about its
impact on health-related quality of life (HRQOL), sleep problems and psychological …

Do you feel itchy? A guide towards diagnosis and measurement of chronic kidney disease-associated pruritus in dialysis patients

L Manenti, E Leuci - Clinical Kidney Journal, 2021 - academic.oup.com
Chronic kidney disease-associated pruritus (CKD-aP) is a potentially distressing condition
that affects a significant proportion of patients with end-stage kidney disease undergoing …

[HTML][HTML] Chronic Kidney Disease–Associated Pruritus and Quality of Life: Learning from Our Patients

V Esteve-Simó, R Perez-Morales… - Journal of clinical …, 2023 - mdpi.com
Chronic kidney disease–associated pruritus is itching directly related to kidney disease that
cannot be explained by any other condition. Despite technological advances in the different …

Epidemiology and burden of chronic kidney disease-associated pruritus

D Kim, C Pollock - Clinical Kidney Journal, 2021 - academic.oup.com
Chronic kidney disease–associated pruritus (CKD-aP) is a common, yet underrecognized
condition in patients with CKD and end-stage kidney disease (ESKD). Real-world …

[HTML][HTML] A year in pharmacology: new drugs approved by the US Food and Drug Administration in 2021

G Kayki-Mutlu, ZS Aksoyalp, L Wojnowski… - Naunyn-schmiedeberg's …, 2022 - Springer
The second year of the COVID-19 pandemic had no adverse effect on the number of new
drug approvals by the US Food and Drug Administration (FDA). Quite the contrary, with a …

[HTML][HTML] Utility of a single itch-related question and the Skindex-10 questionnaire for assessing pruritus and predicting health-related quality of life in patients receiving …

MB Lopes, A Karaboyas, N Sukul, K Tsuruya, I Al Salmi… - Kidney Medicine, 2022 - Elsevier
Rationale & Objective Chronic kidney disease-associated pruritus has been linked with
poorer mental and physical health-related quality of life (HR-QOL) in patients receiving …

Chronic kidney disease-associated pruritus (CKD-aP) is associated with worse quality of life and increased healthcare utilization among dialysis patients

JI Titapiccolo, C Lonati, B Goethel-Paal, AR Bello… - Quality of Life …, 2023 - Springer
Purpose Chronic pruritus significantly impairs hemodialysis patients' health status and
quality of life (QOL) and it is associated with higher mortality rate, more frequent …