Expert opinion on the cough hypersensitivity syndrome in respiratory medicine

AH Morice, E Millqvist, MG Belvisi… - European …, 2014 - Eur Respiratory Soc
In 2011, a European Respiratory Society Task Force embarked on a process to determine
the position and clinical relevance of the cough hypersensitivity syndrome, a disorder …

Antitussive drugs—past, present, and future

PV Dicpinigaitis, AH Morice, SS Birring… - Pharmacological …, 2014 - ASPET
Cough remains a serious unmet clinical problem, both as a symptom of a range of other
conditions such as asthma, chronic obstructive pulmonary disease, gastroesophageal reflux …

Estrogen effects in allergy and asthma

RS Bonds, T Midoro-Horiuti - Current opinion in allergy and …, 2013 - journals.lww.com
Estrogen's role in allergic disease remains complex. As allergic diseases continue to
increase in prevalence and affect women disproportionately, gaining a fuller understanding …

Management of chronic refractory cough

PG Gibson, AE Vertigan - Bmj, 2015 - bmj.com
Chronic refractory cough (CRC) is defined as a cough that persists despite guideline based
treatment. It is seen in 20-46% of patients presenting to specialist cough clinics and it has a …

[HTML][HTML] Update: the search for the human cough receptor

L McGarvey - Lung, 2014 - Springer
Despite the best efforts of basic and applied science, the identity of the human “cough
receptor” remains elusive. The attraction of identifying a single “catch all” cough receptor is …

[HTML][HTML] Clinical features of the urge-to-cough in patients with chronic cough

E Hilton, P Marsden, A Thurston, S Kennedy… - Respiratory …, 2015 - Elsevier
Background The urge-to-cough is a consciously perceived compulsion, previously
investigated in healthy volunteers inhaling irritants. We aimed to characterise the urge-to …

Laryngeal sensory dysfunction in laryngeal hypersensitivity syndrome

AE Vertigan, SL Bone, PG Gibson - Respirology, 2013 - Wiley Online Library
Background and objective Diseases associated with laryngeal dysfunction include chronic
refractory cough (CRC), paradoxical vocal fold movement (PVFM), muscle tension …

[HTML][HTML] Chronic cough hypersensitivity syndrome

AH Morice - Cough, 2013 - Springer
Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip,
and reflux disease. A different paradigm has evolved in which cough is viewed as the …

Pharmacodynamic modeling of cough responses to capsaicin inhalation calls into question the utility of the C5 end point

ECY Hilton, PG Baverel, A Woodcock… - Journal of allergy and …, 2013 - Elsevier
Background Inhaled capsaicin elicits cough reproducibly in human subjects and is widely
used in the study of cough and antitussive therapies. However, the traditional end points C2 …

Airway reflux

N Johnston, F Ondrey, R Rosen… - Annals of the New …, 2016 - Wiley Online Library
An ever‐increasing number of adult and pediatric disorders have been shown to be
influenced or caused by airway reflux. This has become a controversial and complicated …