Melanins provide fungi protection from environmental stressors, support their ecological
roles, and can confer virulence in pathogens. While the function, structure, and synthesis of …

Psilocybin and psilocin, two psychoactive components found in “magic mushrooms,” have
therapeutic potential in a number of mental health disorders without the addictiveness and …

Protists, a highly diverse group of microscopic eukaryotic organisms distinct from fungi,
animals and plants, exert crucial roles within the earth's biosphere. However, the genomes …

Using next-generation sequencing (NGS), we developed and validated a whole-genome
sequencing (WGS)-based clinical test for fungal species identification on clinical isolates …

The X-ray crystal structures of soybean lipoxygenase (LOX) and rabbit 15-LOX were
reported in the 1990s. Subsequent 3D structures demonstrated a conserved U-like shape of …

Fungi are notoriously prolific producers of secondary metabolites including nonribosomal
peptides (NRPs). The structural complexity of NRPs grants them interesting activities such …

Nosocomial clusters of fungal infections, whilst uncommon, cannot be predicted and are
associated with significant morbidity and mortality. Here, we review reports of nosocomial …

Analyses of fungal genomes of escalate from biological and evolutionary investigations. The
biochemical analyses of putative enzymes will inevitably lag behind and only a selection will …

Recent improvements in microbiology and molecular epidemiology were largely stimulated
by whole-genome sequencing (WGS), which provides an unprecedented resolution in …

Invasive fungal diseases (IFDs) comprise a growing healthcare burden, especially given the
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …