A potential link between visceral obesity and risk of Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Neurochemical …, 2023 - Springer
Alzheimer's disease (AD) is the most common type of dementia characterized by the
deposition of amyloid beta (Aβ) plaques and tau-neurofibrillary tangles in the brain. Visceral …

[HTML][HTML] Zinc in cognitive impairment and aging

R Sun, J Wang, J Feng, B Cao - Biomolecules, 2022 - mdpi.com
Zinc, an essential micronutrient for life, was first discovered in 1869 and later found to be
indispensable for the normal development of plants and for the normal growth of rats and …

Experimental approaches for altering the expression of Abeta‐degrading enzymes

DA Loeffler - Journal of neurochemistry, 2023 - Wiley Online Library
Cerebral clearance of amyloid β‐protein (Aβ) is decreased in early‐onset and late‐onset
Alzheimer's disease (AD). Aβ is cleared from the brain by enzymatic degradation and by …

[HTML][HTML] Identification of a novel Wnt antagonist based therapeutic and diagnostic target for Alzheimer's disease using a stem cell-derived model

M Patil, N Gamit, A Dharmarajan, G Sethi, S Warrier - Bioengineering, 2023 - mdpi.com
Currently, all the existing treatments for Alzheimer's disease (AD) fail to stall progression due
to longer duration of time between onset of the symptoms and diagnosis of the disease …

[HTML][HTML] Early-stage differentiation between Alzheimer's disease and frontotemporal lobe degeneration: Clinical, neuropsychology, and neuroimaging features

P Li, W Quan, Z Wang, Y Liu, H Cai, Y Chen… - Frontiers in Aging …, 2022 - frontiersin.org
Background Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD) are
the two most common forms of neurodegenerative dementia. Although both of them have …

Co-administration of dl-3-n-butylphthalide and neprilysin is neuroprotective in Alzheimer disease associated with mild traumatic brain injury.

ZG Wang, A Sharma, L Feng, DF Muresanu… - International Review …, 2023 - europepmc.org
dl-3-n-Butylphthalide is a potent synthetic Chinese celery extract that is highly efficient in
inducing neuroprotection in concussive head injury (CHI), Parkinson's disease, Alzheimer's …

Pathophysiological association of alzheimer's disease and hypertension: A clinical concern for elderly population

Q Yao, K Jiang, F Lin, T Zhu, NH Khan… - Clinical Interventions in …, 2023 - Taylor & Francis
Abstract Alzheimer's disease (AD), the most common cause of dementia and the fifth leading
cause of death in the adult population has a complex pathophysiological link with …

The Effect of Prenatal Hypoxia on the Metabolism of Amyloid Precursor Protein

NN Nalivaeva - Neurochemical Journal, 2022 - Springer
The constitutive transmembrane amyloid precursor protein (APP) is not only one of the
factors contributing to the pathogenesis of Alzheimer's disease (AD) but also an important …

Amyloid Precursor Protein, Alpha-, Beta-and Gamma-Secretases Expression in Penumbra Cells after Photothrombotic Stroke. Evaluation of the Neuroprotective Effect …

S Sharifulina, V Guzenko, A Logvinov, A Khaitin… - 2022 - preprints.org
Photothrombotic stroke (PTS) stimulates the level of N-and C-terminal fragments of Amyloid
precursor protein (APP) growth in the cytoplasm of ischemic penumbra cells not earlier but …