[HTML][HTML] Oral squamous cell carcinomas: state of the field and emerging directions

Y Tan, Z Wang, M Xu, B Li, Z Huang, S Qin… - International journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …

[HTML][HTML] PI3K inhibitors in cancer: clinical implications and adverse effects

R Mishra, H Patel, S Alanazi, MK Kilroy… - International journal of …, 2021 - mdpi.com
The phospatidylinositol-3 kinase (PI3K) pathway is a crucial intracellular signaling pathway
which is mutated or amplified in a wide variety of cancers including breast, gastric, ovarian …

Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action …

JAEM Zecha, JE Raber-Durlacher, RG Nair… - Supportive Care in …, 2016 - Springer
Purpose There is a large body of evidence supporting the efficacy of low level laser therapy
(LLLT), more recently termed photobiomodulation (PBM), for the management of oral …

[HTML][HTML] Evidence-based treatment options in recurrent and/or metastatic squamous cell carcinoma of the head and neck

A Argiris, KJ Harrington, M Tahara, J Schulten… - Frontiers in …, 2017 - frontiersin.org
The major development of the past decade in the first-line treatment of recurrent and/or
metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) was the …

Phosphatidylinositol 3 kinase (PI3K) inhibitors as new weapon to combat cancer

FM Elmenier, DS Lasheen, KAM Abouzid - European journal of medicinal …, 2019 - Elsevier
Abstract Phosphatidylinositol-3 kinase (PI3K) pathway is one of the most frequently activated
pathogenic signaling cascades in human malignancies. PI3K is genetically mutated or …

Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials

HS Budi, B Farhood - Environmental research, 2023 - Elsevier
Oral cancers consist of squamous cell carcinoma (SCC) and other malignancies in the
mouth with varying degrees of invasion and differentiation. For many years, different …

Quercetin loaded nanoparticles in targeting cancer: recent development

M Vinayak, AK Maurya - Anti-Cancer Agents in Medicinal …, 2019 - ingentaconnect.com
The spread of metastatic cancer cell is the main cause of death worldwide. Cellular and
molecular basis of the action of phytochemicals in the modulation of metastatic cancer …

Could the biological robustness of low level laser therapy (Photobiomodulation) impact its use in the management of mucositis in head and neck cancer patients

ST Sonis, S Hashemi, JB Epstein, RG Nair… - Oral oncology, 2016 - Elsevier
Low level laser therapy (LLLT) has been noted to be effective in mitigating the development
of oral mucositis among patients being treated with chemoradiation for cancers of the head …

An update on the implications of cyclin D1 in oral carcinogenesis

P Ramos‐Garcia, JA Gil‐Montoya, C Scully… - Oral …, 2017 - Wiley Online Library
Cyclin D1 promotes cell cycle progression during G1 phase, a key event in G1‐S transition.
The protein is encoded by gene CCND 1, located in chromosomal band 11q13. Cyclin D1 …

[HTML][HTML] Current insights and progress in the clinical management of head and neck cancer

MN Amaral, P Faísca, HA Ferreira, MM Gaspar… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer (HNC) incidence has been steadily increasing
since the 1990s. While the multimodal treatment approach for localized HNC is well …