Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
Advances in molecular targeted therapies to increase efficacy of (chemo) radiation therapy
K Viktorsson, T Rieckmann, M Fleischmann… - Strahlentherapie und …, 2023 - Springer
Recent advances in understanding the tumor's biology in line with a constantly growing
number of innovative technologies have prompted characterization of patients' individual …
number of innovative technologies have prompted characterization of patients' individual …
A comprehensive review on role of Aurora kinase inhibitors (AKIs) in cancer therapeutics
D Gupta, M Kumar, S Saifi, S Rawat… - International Journal of …, 2024 - Elsevier
Aurora kinases (AURKs) are a family of serine/threonine protein kinases that have a crucial
role in cell cycle process mainly in the event of chromosomal segregation, centrosome …
role in cell cycle process mainly in the event of chromosomal segregation, centrosome …
Social, ethical and treatment related problems faced by healthcare workers in the care of head and neck cancer patients: A narrative review from the bioethics …
Head and neck cancer (HNC) presents a variety of ethical difficulties for an oncologist
involved in screening, diagnosis, treatment, and rehabilitation that are challenging to …
involved in screening, diagnosis, treatment, and rehabilitation that are challenging to …
[HTML][HTML] Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1
A Oetting, S Christiansen, F Gatzemeier… - Clinical and …, 2023 - Elsevier
Objectives In head and neck squamous cell carcinoma (HNSCC), tumors negative for
Human Papillomavirus (HPV) remain a difficult to treat entity and the morbidity of current …
Human Papillomavirus (HPV) remain a difficult to treat entity and the morbidity of current …
Comprehensive Insights into Oral Squamous Cell Carcinoma: Diagnosis, Pathogenesis, and Therapeutic Advances
D Jagadeesan, KV Sathasivam, NK Fuloria… - … -Research and Practice, 2024 - Elsevier
Oral squamous cell carcinoma (OSCC) is considered the most common type of head and
neck squamous cell carcinoma (HNSCC) as it holds 90% of HNSCC cases that arise from …
neck squamous cell carcinoma (HNSCC) as it holds 90% of HNSCC cases that arise from …
Efficacy of depatuxizumab mafodotin (ABT-414) in preclinical models of head and neck cancer
L Mani, A Naveed, A McAdoo, E Rosenthal… - …, 2024 - academic.oup.com
Epidermal growth factor receptor (EGFR) is highly expressed in 80–90% of head and neck
squamous cell carcinomas (HNSCCs), making it an ideal target for antibody–drug …
squamous cell carcinomas (HNSCCs), making it an ideal target for antibody–drug …
Targeting BRD4: Potential therapeutic strategy for head and neck squamous cell carcinoma
V Yongprayoon, N Wattanakul… - Oncology …, 2024 - spandidos-publications.com
As a member of BET (bromodomain and extra-terminal) protein family, BRD4 (bromodomain‑
containing protein 4) is a chromatin‑associated protein that interacts with acetylated histones …
containing protein 4) is a chromatin‑associated protein that interacts with acetylated histones …
An epidermal growth factor receptor‐targeting immunotoxin based on IgG shows potent antitumor activity against head and neck cancer
M Huang, J Park, J Seo, S Ko, YH Yang… - The FASEB …, 2024 - Wiley Online Library
The epidermal growth factor receptor (EGFR) is an important target for cancer therapies.
Many head and neck cancer (HNC) cells have been reported to overexpress EGFR; …
Many head and neck cancer (HNC) cells have been reported to overexpress EGFR; …
Radiation-induced skin injury in the head and neck region: pathogenesis, clinics, prevention, treatment considerations and proposal for management algorithm
J Pazdrowski, J Gornowicz-Porowska… - Reports of Practical …, 2024 - journals.viamedica.pl
Worldwide increase o fh ead and neck cancers ranks thes em alignancies among top
causes of cancer i nh uman population. Radiation induced skin injury (RISI) is one of th em …
causes of cancer i nh uman population. Radiation induced skin injury (RISI) is one of th em …