Role of sleep deprivation in immune-related disease risk and outcomes
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …
Periphery and brain, innate and adaptive immunity in Parkinson's disease
Parkinson's disease (PD) is a neurodegenerative disorder where alpha-synuclein plays a
central role in the death and dysfunction of neurons, both, in central, as well as in the …
central role in the death and dysfunction of neurons, both, in central, as well as in the …
The gut–brain axis and its relation to Parkinson's disease: a review
EM Klann, U Dissanayake, A Gurrala… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease is a chronic neurodegenerative disease characterized by the
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …
The pathogenesis of Parkinson's disease
Parkinson's disease is a progressive neurodegenerative condition associated with the
deposition of aggregated α-synuclein. Insights into the pathogenesis of Parkinson's disease …
deposition of aggregated α-synuclein. Insights into the pathogenesis of Parkinson's disease …
Glymphatic system dysfunction and sleep disturbance may contribute to the pathogenesis and progression of Parkinson's disease
A Massey, MK Boag, A Magnier, DPCF Bispo… - International journal of …, 2022 - mdpi.com
Parkinson's disease (PD) is a multisystem alpha-synucleinopathic neurodegenerative
disease and the most prevalent neurodegenerative disorder after Alzheimer's disease with a …
disease and the most prevalent neurodegenerative disorder after Alzheimer's disease with a …
Circadian disruption and sleep disorders in neurodegeneration
Y Shen, Q Lv, W Xie, S Gong, S Zhuang, J Liu… - Translational …, 2023 - Springer
Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …
Clinical and imaging markers of prodromal Parkinson's disease
E Hustad, JO Aasly - Frontiers in neurology, 2020 - frontiersin.org
The diagnosis of Parkinson's disease (PD) relies on the clinical effects of dopamine
deficiency, including bradykinesia, rigidity and tremor, usually manifesting asymmetrically …
deficiency, including bradykinesia, rigidity and tremor, usually manifesting asymmetrically …
Roles of clock genes in the pathogenesis of Parkinson's disease
AD Shkodina, SC Tan, MM Hasan… - Ageing Research …, 2022 - Elsevier
Parkinson's disease (PD) is a common motor disorder that has become increasingly
prevalent in the ageing population. Recent works have suggested that circadian rhythms …
prevalent in the ageing population. Recent works have suggested that circadian rhythms …
Research evidence of the role of the glymphatic system and its potential pharmacological modulation in neurodegenerative diseases
JP Verghese, A Terry, ER de Natale… - Journal of Clinical …, 2022 - mdpi.com
The glymphatic system is a unique pathway that utilises end-feet Aquaporin 4 (AQP4)
channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid …
channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid …
[HTML][HTML] REM sleep behavior disorder (RBD)
MT Hu - Neurobiology of Disease, 2020 - Elsevier
Since its first description in 1986 by Dr. Carlos Schenck, and his group's subsequent report
of the delayed emergence of a Parkinsonian disorder in idiopathic RBD patients one decade …
of the delayed emergence of a Parkinsonian disorder in idiopathic RBD patients one decade …