Optimization and structural stability of gold nanoparticle–antibody bioconjugates

RT Busch, F Karim, J Weis, Y Sun, C Zhao… - ACS …, 2019 - ACS Publications
Gold nanoparticles (AuNPs) bound with biomolecules have emerged as suitable biosensors
exploiting unique surface chemistries and optical properties. Many efforts have focused on …

Stochastic DNA dual-walkers for ultrafast colorimetric bacteria detection

H Yang, M Xiao, W Lai, Y Wan, L Li, H Pei - Analytical chemistry, 2020 - ACS Publications
Rapid, sensitive, and reliable pathogen detection is growing in importance in human health
and safety. In this work, we report a stochastic DNA dual-walker-based colorimetric …

Chiral surface of nanoparticles determines the orientation of adsorbed transferrin and its interaction with receptors

X Wang, M Wang, R Lei, SF Zhu, Y Zhao, C Chen - ACS nano, 2017 - ACS Publications
When nanoparticles are exposed to a physiological environment, a “protein corona” is
formed that greatly determines their biological fate. Adsorption of proteins could be …

Nanoparticle ligand exchange and its effects at the nanoparticle–cell membrane interface

X Wang, X Wang, X Bai, L Yan, T Liu, M Wang… - Nano …, 2018 - ACS Publications
The nanoparticle (nano)–cell membrane interface is one of the most important interactions
determining the fate of nanoparticles (NPs), which can stimulate a series of biological …

Identification and interaction mechanism of protein corona on silver nanoparticles with different sizes and the cellular responses

Z Zhao, G Li, QS Liu, W Liu, G Qu, L Hu, Y Long… - Journal of hazardous …, 2021 - Elsevier
With the potential biomedical applications of nanomaterials such as silver nanoparticles
(SNPs), nanotoxicity concerns are growing, and the importance of NP and protein …

Functionalized fluorescent nanomaterials for sensing pollutants in the environment: A critical review

L Walekar, T Dutta, P Kumar, YS Ok, S Pawar… - TrAC Trends in …, 2017 - Elsevier
Quantitation of environmental pollutants has gained momentum due to its widespread
requirement in the fields of clinical research, occupational hygiene, public health, and …

Comprehensive multispectroscopic analysis on the interaction and corona formation of human serum albumin with gold/silver alloy nanoparticles

A Selva Sharma, M Ilanchelian - The Journal of Physical …, 2015 - ACS Publications
In the present investigation, we have systematically studied the binding mechanism of model
protein human serum albumin (HSA) with gold/silver alloy nanoparticles (Au/Ag NPs) using …

A centrifugation-based physicochemical characterization method for the interaction between proteins and nanoparticles

A Bekdemir, F Stellacci - Nature communications, 2016 - nature.com
Nanomedicine requires in-depth knowledge of nanoparticle–protein interactions. These
interactions are studied with methods limited to large or fluorescently labelled nanoparticles …

Magnetothermal regulation of in vivo protein corona formation on magnetic nanoparticles for improved cancer nanotherapy

T Zhang, G Li, Y Miao, J Lu, N Gong, Y Zhang, Y Sun… - Biomaterials, 2021 - Elsevier
Engineering the protein corona (PC) on nanodrugs is emerging as an effective approach to
improve their pharmacokinetics and therapeutic efficacy, but conventional in vitro pre …

Electrostatic interactions and protein competition reveal a dynamic surface in gold nanoparticle–protein adsorption

A Wang, YR Perera, MB Davidson… - The Journal of Physical …, 2016 - ACS Publications
Gold nanoparticle–(AuNP−) protein conjugates are potentially useful in a broad array of
diagnostic and therapeutic applications, but the physical basis of the simultaneous …