Potential therapeutic application of chondroitin sulfate/dermatan sulfate

S Yamada, K Sugahara - Current Drug Discovery Technologies, 2008 - ingentaconnect.com
Glycosaminoglycans (GAGs) are complex polysaccharides, which play important roles in
cell growth, differentiation, morphogenesis, cell migration, and bacterial/viral infections …

A microchip for quantitative analysis of CNS axon growth under localized biomolecular treatments

J Park, S Kim, SI Park, Y Choe, J Li, A Han - Journal of neuroscience …, 2014 - Elsevier
Growth capability of neurons is an essential factor in axon regeneration. To better
understand how microenvironments influence axon growth, methods that allow spatial …

NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia

Q Gao, J Lu, Y Huo, N Baby, EA Ling, ST Dheen - Neuroscience, 2010 - Elsevier
Activation of microglial cells, the resident immune cells of the CNS causes neurotoxicity
through the release of a wide array of inflammatory mediators including proinflammatory …

蛋鸡卵巢CHST11 基因CDS 序列分析

陈建伟, 李鹏飞, 姜晓龙, 赵妙妙, 姚晓磊… - 山西农业大学学报: 自然 …, 2014 - cqvip.com
根据NCBI 上已公布其他物种CHST11 基因的mRNA 序列设计蛋鸡特异性引物, 应用RT-PCR
方法从其卵巢卵泡中扩增出CHST11 的CDS 全序列. 结果表明: CHST11 …

中枢神经损伤研究进展

尹小磊, 袁容娣, 叶剑 - 国际眼科杂志, 2010 - cqvip.com
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NG2 与中枢神经系统疾病研究新进展

赵培园, 郭泽云, 吴春云 - 神经解剖学杂志, 2011 - cqvip.com
NG2 是一种硫酸软骨素蛋白多糖(chondroitin sulphate peoteoglycan, CSPG),
在发育及成熟哺乳动物中枢神经系统中广泛表达. 表达NG2 的细胞根据其密度, 分布 …

Central nervous system extracellular matrix as a therapeutic bioscaffold for central nervous system injury

CJ Medberry - 2014 - d-scholarship.pitt.edu
Traumatic central nervous system (CNS) injuries lack effective treatment options and
typically result in irrecoverable tissue damage and lifelong neurologic impairment. An ideal …

Chondroitin Sulfate as a Bioactive Macromolecule for Advanced Biological Applications and Therapies

N Volpi - Biomaterials from Nature for Advanced Devices and …, 2016 - Wiley Online Library
Glycosaminoglycans (GAGs) are acidic, highly sulfated, complex, linear, natural
heteropolysaccharides distributed among all organisms and composed of a variable number …

Use of Enabling Technologies in Combination with Human Pluripotent Stem Cells to Study Neural Differentiation and Neurite Outgrowth

D TAMS - 2014 - etheses.dur.ac.uk
Regeneration of human central nervous system (CNS) neurons is limited due to the
inhibitory environment that forms post injury known as the glial scar. Reactive astrocytes …

Acceleration of microglial clearance function by small TREM2-activating anionic disaccharides

V Nunes de Paiva - 2014 - bonndoc.ulb.uni-bonn.de
Triggering receptor expressed on myeloid cells-2 (TREM2) is an innate immune receptor,
which is expressed on myeloid cells, like microglia inside the central nervous system …