Knee osteoarthritis (KOA) is a degenerative disease, making a unique contribution to
chronic pain, edema, and limited mobility of knee joint. Traditional Chinese Medicine (TCM) …

Bone is an alive and dynamic organ that is well-differentiated and originated from
mesenchymal tissues. Bone undergoes continuous remodeling during the lifetime of an …

Objective Osteoarthritis (OA) is characterized by cartilage degeneration and inflammation.
Procyanidin B2 (PCB2), a natural flavonoid compound, exhibits potential anti-inflammatory …

Osteoarthritis (OA) is a bone and joint disease characterized by progressive cartilage
degradation. In the face of global trends of population aging, OA is expected to become the …

Pathological changes, such as articular cartilage degeneration, destruction, and
hyperosteogeny, are regarded as the main features of osteoarthritis (OA). Sinomenine (SIN) …

Osteoarthritis (OA) affects more than 300 million individuals globally, with higher prevalence
in women than in men. In addition, OA affects women and men differently, with women …

Circular RNAs (circRNAs) are currently classed as non-coding RNAs that, unlike the better
known canonical linear RNAs, form a covalently closed continuous loop without 5′ or 3 …

Purpose: To explore the regulatory mechanism of miR-137 and transcription factor 4 (TCF4)
in the progression of osteoarthritis (OA). Patients and Methods: The expressions of miR-137 …

Huoxuezhitong capsule (HXZT, activating blood circulation and relieving pain capsule), has
been applied for osteoarthritis since 1974. It consists of Angelica sinensis (Oliv.) Diels …

Temporomandibular joint osteoarthritis (TMJ‑OA) is a common disease with a high level of
inflammation in the joint micro‑environment and cartilage degradation. Anti‑inflammation …