Background: Androgen deprivation therapy (ADT) is a mainstay of prostate cancer in both
adjuvant and palliative settings. Since androgens are crucial for functional status and …

Approximately 23% of metastatic castration-resistant prostate cancers (mCRPC) harbor
deleterious aberrations in DNA repair genes. Poly (ADP-ribose) polymerase (PARP) …

Androgen receptors (ARs) play key roles in prostate cancer (PCa) progression and
castration-resistant prostate cancer (CRPC) resistance to drug therapy. SET and MYND …

Antineoplastic therapies for prostate cancer (PCa) have traditionally centered around the
androgen receptor (AR) pathway, which has demonstrated a significant role in oncogenesis …

Prostate cancer is a disease that often occurs in elderly men. Androgen receptor signaling
pathway runs through the occurrence and development of prostate cancer. Thereby …

Abstract Luminal Androgen Receptor Breast Cancers (LAR BCs) are characterized by a
triple negative phenotype and by the expression of Androgen Receptor (AR), coupled with …

Stereotactic ablative body radiotherapy (SABR) is currently used as a salvage intervention
for men with oligometastatic prostate cancer (PC), and increasingly so since the results of …

Recently, the androgen receptor has been found as a potential prognostic index and
therapeutic target for breast cancer. To reveal the current research status and hotspots in …

Prostate cancer (CaP) is one of the most prevalent male malignancies, accounting for a
considerable number of annual mortalities. However, the prompt identification of early-stage …

Plakophilin (PKP1) 1 is a member of the arm‐repeat family of catenins and acts as a
structural component of desmosomes, which are important stabilizers of cell–cell adhesion …