The biology of the prostate gland is intimately linked with the androgens and the androgen
receptor (AR), which are essential in the regulation of male sexual development and …

Introduction: Prostate cancer (PCa) is the second most common malignancy in men. Despite
multidisciplinary treatments, patients with PCa continue to experience poor prognoses and …

Abstract G-1, a GPER1 agonist, was shown to inhibit the growth of castration-resistant
mouse xenografts but not their parental androgen-dependent tumors. It is currently unknown …

The androgen receptor AR antagonists, such as enzalutamide and apalutamide, are efficient
therapeutics for the treatment of prostate cancer (PCa). Even though they are effective at …

Prostate cancer (CaP) is one of the most prevalent male malignancies, accounting for a
considerable number of annual mortalities. However, the prompt identification of early-stage …

There is increased incidence of prostate cancer (PC) among World Trade Center (WTC)-
exposed responders and community members, with preliminary evidence suggestive of …

Purpose: Much progress has been made by directing against AR pathway in the treatment of
prostate cancer in past decades. However, AR-interactors related metastatic castration …

Purpose To assess the role of the p160 family, AR, and AR-V7 in different initial
presentations of prostate cancer and their association with clinical endpoints related to …

Androgen deprivation therapy (ADT) remains the cornerstone of advanced prostate cancer
treatment. However, the progression towards castration-resistant prostate cancer is …

Cancer diagnosis using cell-free DNA (cfDNA) has potential to improve treatment and
survival but has several technical limitations. Here, we show that tumor-associated …