In its early stages, symptoms of chronic kidney disease (CKD) are usually not apparent.
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …

Objective The understanding of systemic lupus erythematosus (SLE) and lupus nephritis
(LN) pathogenesis remains incomplete. This review assessed LN development in SLE …

Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the
loss of tolerance to nuclear self antigens, the production of pathogenic autoantibodies and …

Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the
management of SLE because of the difficulty in diagnosing its subclinical onset and …

Systemic lupus erythematosus is a potentially fatal autoimmune disease. Although
interleukin-17 (IL-17) has been linked to human lupus and mouse models of this disease, it …

Background Recent studies indicate a central role for the IL-23/IL-17 axis in the
pathogenesis of lupus nephritis (LN) but the importance in the context of treatment outcome …

The search for lupus biomarkers to diagnose, monitor, stratify, and predict individual
response to therapy is currently more intense than ever before. This effort is essential for …

Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

Lupus nephritis (LN) is one of the most serious complications of systemic lupus
erythematosus (SLE) since it is the major predictor of poor prognosis. In susceptible …

Management of patient with Lupus Nephritis (LN) continues to remain a challenge for the
treating physicians because of considerable morbidity and even mortality. The search of …