[HTML][HTML] Antibody and Cell-Based Therapies against Virus-Induced Cancers in the Context of HIV/AIDS
J Joseph, G Sandel, R Kulkarni, R Alatrash, BB Herrera… - Pathogens, 2023 - mdpi.com
Infectious agents, notably viruses, can cause or increase the risk of cancer occurrences.
These agents often disrupt normal cellular functions, promote uncontrolled proliferation and …
These agents often disrupt normal cellular functions, promote uncontrolled proliferation and …
Broadly neutralizing antibodies for HIV prevention: a comprehensive review and future perspectives
S Mahomed - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
The human immunodeficiency virus (HIV) epidemic remains a formidable global health
concern, with 39 million people living with the virus and 1.3 million new infections reported …
concern, with 39 million people living with the virus and 1.3 million new infections reported …
Glycan-Imprinted Nanoparticle as Artificial Neutralizing Antibody for Efficient HIV-1 Recognition and Inhibition
J Zhou, L Wang, X Liu, Y Gai, M Dong, C Wang… - Nano Letters, 2024 - ACS Publications
The HIV-1 envelope is a heavily glycosylated class 1 trimeric fusion protein responsible for
viral entry into CD4+ immune cells. Developing neutralizing antibodies against the specific …
viral entry into CD4+ immune cells. Developing neutralizing antibodies against the specific …
[HTML][HTML] The Use of Broadly Neutralizing Antibodies (bNAbs) in HIV-1 Treatment and Prevention
JJ Thavarajah, BL Hønge, CM Wejse - Viruses, 2024 - mdpi.com
Background: Although antiretroviral therapy (ART) effectively halts disease progression in
HIV infection, the complete eradication of the virus remains elusive. Additionally, challenges …
HIV infection, the complete eradication of the virus remains elusive. Additionally, challenges …
[HTML][HTML] Rational Design and Characterization of Trispecific Antibodies Targeting the HIV-1 Receptor and Envelope Glycoprotein
J Liang, L Zhai, Z Liang, X Chen, Y Jiang, Y Lin, S Feng… - Vaccines, 2023 - mdpi.com
Multitudinous broadly neutralizing antibodies (bNAbs) against HIV-1 have been developed
as novel antiviral prophylactic and therapeutic agents. Combinations of bNAbs are generally …
as novel antiviral prophylactic and therapeutic agents. Combinations of bNAbs are generally …
A library-on-library screen reveals the breadth expansion landscape of a broadly neutralizing betacoronavirus antibody
Broadly neutralizing antibodies (bnAbs) typically evolve cross-reactivity breadth through
acquiring somatic hypermutations. While evolution of breadth requires improvement of …
acquiring somatic hypermutations. While evolution of breadth requires improvement of …