Genetics, pathobiology and therapeutic opportunities of polycystic liver disease

P Olaizola, PM Rodrigues… - Nature Reviews …, 2022 - nature.com
Polycystic liver diseases (PLDs) are inherited genetic disorders characterized by
progressive development of intrahepatic, fluid-filled biliary cysts (more than ten), which …

[HTML][HTML] Polycystic liver disease: classification, diagnosis, treatment process, and clinical management

ZY Zhang, ZM Wang, Y Huang - World journal of hepatology, 2020 - ncbi.nlm.nih.gov
Polycystic liver disease (PLD) is a rare hereditary disease that independently exists in
isolated PLD, or as an accompanying symptom of autosomal dominant polycystic kidney …

Polycystic liver disease: pathophysiology, diagnosis and treatment

LF Norcia, EM Watanabe… - Hepatic Medicine …, 2022 - Taylor & Francis
Polycystic liver disease (PLD) is a clinical condition characterized by the presence of more
than 10 cysts in the liver. It is a rare disease Of genetic etiology that presents as an isolated …

Cholestasis due to USP53 deficiency

LN Bull, R Ellmers, P Foskett… - Journal of pediatric …, 2021 - journals.lww.com
Objectives: Although a number of genetic forms of cholestasis have been identified, the
genetic etiology of disease remains unidentified in a subset of cholestasis patients. Methods …

[HTML][HTML] Liver transplantation for rare liver diseases and rare indications for liver transplant

M Finotti, P Auricchio, A Vitale, E Gringeri… - Translational …, 2021 - ncbi.nlm.nih.gov
Liver transplantation (LT) is currently considered the gold standard treatment for end-stage
liver failure. Compared to the first decades of its use, LT is associated with lower comorbidity …

Benign liver lesions 2022: Guideline for clinical practice of Associazione Italiana Studio del Fegato (AISF), Società Italiana di Radiologia Medica e Interventistica …

M Pompili, F Ardito, E Brunetti, G Cabibbo… - Digestive and Liver …, 2022 - Elsevier
Benign liver lesions are increasingly diagnosed in daily clinical practice due to the growing
use of imaging techniques for the study of the abdomen in patients who have non-specific …

Molecular components and polarity of radial glial cells during cerebral cortex development

FS Chou, R Li, PS Wang - Cellular and Molecular Life Sciences, 2018 - Springer
Originating from ectodermal epithelium, radial glial cells (RGCs) retain apico-basolateral
polarity and comprise a pseudostratified epithelial layer in the developing cerebral cortex …

Cystic lesions of the liver—a review

M Pitchaimuthu, M Duxbury - Current problems in surgery, 2017 - Elsevier
Cystic lesions of the liver may be classified as parasitic and nonparasitic. The main parasitic
cystic lesion of the liver is hydatid disease. Nonparasitic lesions are again divided into …

[HTML][HTML] Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice

J Chen, NC Cheng, JA Boland, K Liu, JG Kench… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Background & aims Loss of primary cilia in epithelial cells is known to cause cystic diseases
of the liver and kidney. We have previously shown that during experimental and human …

Relationships between congenital peritoneopericardial diaphragmatic hernia or congenital central diaphragmatic hernia and ductal plate malformations in dogs and …

LM Seibert, SA Center, JF Randolph… - Journal of the …, 2021 - Am Vet Med Assoc
OBJECTIVE To characterize the association between peritoneopericardial diaphragmatic
hernia (PPDH) or congenital central diaphragmatic hernia (CCDH) and ductal plate …