[HTML][HTML] The potential of metabolomics in biomedical applications
V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Current high-throughput technologies have allowed the discovery of relevant metabolites …
[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism
PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …
[HTML][HTML] Systems biology and multi-omics integration: viewpoints from the metabolomics research community
The use of multiple omics techniques (ie, genomics, transcriptomics, proteomics, and
metabolomics) is becoming increasingly popular in all facets of life science. Omics …
metabolomics) is becoming increasingly popular in all facets of life science. Omics …
Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …
sources is currently an advancing area in industrial research. The model yeast …
Yeast systems biology: model organism and cell factory
J Nielsen - Biotechnology journal, 2019 - Wiley Online Library
For thousands of years, the yeast Saccharomyces cerevisiae (S. cerevisiae) has served as a
cell factory for the production of bread, beer, and wine. In more recent years, this yeast has …
cell factory for the production of bread, beer, and wine. In more recent years, this yeast has …
Genome-scale metabolic network reconstruction of model animals as a platform for translational research
Genome-scale metabolic models (GEMs) are used extensively for analysis of mechanisms
underlying human diseases and metabolic malfunctions. However, the lack of …
underlying human diseases and metabolic malfunctions. However, the lack of …
[HTML][HTML] Drosophila as a model for ageing
MDW Piper, L Partridge - Biochimica et Biophysica Acta (BBA)-Molecular …, 2018 - Elsevier
Drosophila melanogaster has been a key model in developing our current understanding of
the molecular mechanisms of ageing. Of particular note is its role in establishing the …
the molecular mechanisms of ageing. Of particular note is its role in establishing the …
Metabolic control of nitrogen fixation in rhizobium-legume symbioses
Rhizobia induce nodule formation on legume roots and differentiate into bacteroids, which
catabolize plant-derived dicarboxylates to reduce atmospheric N2 into ammonia. Despite …
catabolize plant-derived dicarboxylates to reduce atmospheric N2 into ammonia. Despite …
Metabolomics signatures in type 2 diabetes: a systematic review and integrative analysis
Y Sun, HY Gao, ZY Fan, Y He… - The Journal of Clinical …, 2020 - academic.oup.com
Objective Metabolic signatures have emerged as valuable signaling molecules in the
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …
Mechanisms and mathematical modeling of ROS production by the mitochondrial electron transport chain
S Chenna, WJH Koopman… - … of Physiology-Cell …, 2022 - journals.physiology.org
Reactive oxygen species (ROS) are recognized both as damaging molecules and
intracellular signaling entities. In addition to its role in ATP generation, the mitochondrial …
intracellular signaling entities. In addition to its role in ATP generation, the mitochondrial …