[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

[HTML][HTML] Sex-gender differences in irritable bowel syndrome

YS Kim, N Kim - Journal of neurogastroenterology and motility, 2018 - ncbi.nlm.nih.gov
Because of the sex-gender differences that are shown in a diversity of physiological and
psychological factors, it can be speculated that the clinical presentation of symptoms as well …

Sex differences in pharmacokinetics predict adverse drug reactions in women

I Zucker, BJ Prendergast - Biology of sex differences, 2020 - Springer
Background Women experience adverse drug reactions, ADRs, nearly twice as often as
men, yet the role of sex as a biological factor in the generation of ADRs is poorly understood …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced drug delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

Gender differences in the effects of cardiovascular drugs

J Tamargo, G Rosano, T Walther… - European Heart …, 2017 - academic.oup.com
An initiation-promotion protocol was used to test the hypothesis that unleaded gasoline (UG)
vapor acts as a liver tumor promoter in female mice under exposure conditions in which UG …

Sex differences in the psychopharmacological treatment of depression

JJ Sramek, MF Murphy, NR Cutler - Dialogues in clinical …, 2016 - Taylor & Francis
Although a number of studies have observed that females respond better to serotonergic
antidepressants than males and that postmenopausal females have a diminished response …

Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology

I Erlund - Nutrition research, 2004 - Elsevier
The bioactivities, dietary sources, bioavailability, metabolism, and epidemiology of 3
flavonoids, quercetin, hesperetin, and naringenin, are reviewed. The use of their plasma …

A growing role for gender analysis in air pollution epidemiology

JE Clougherty - Environmental health perspectives, 2010 - ehp.niehs.nih.gov
Objective Epidemiologic studies of air pollution effects on respiratory health report significant
modification by sex, although results are not uniform. Importantly, it remains unclear whether …

The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes

C Schiborr, A Kocher, D Behnam… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Curcumin revealed various health‐beneficial properties in numerous studies.
However its bioavailability is low due to its limited intestinal uptake and rapid metabolism …

Sex differences in pharmacokinetics and pharmacodynamics

M Gandhi, F Aweeka, RM Greenblatt… - Annu. Rev. Pharmacol …, 2004 - annualreviews.org
The importance of reviewing and studying sex-based differences in pharmacologic
parameters is demonstrated by the increasing data on gender variation in drug efficacy and …