[HTML][HTML] Cancer stem cells and tumorigenesis

P Zhu, Z Fan - Biophysics reports, 2018 - Springer
Cancer is one of the most serious diseases all over the world, and the cancer stem cell
(CSC) model accounts for tumor initiation, metastasis, drug resistance, and relapse. The …

[HTML][HTML] Infection by high-risk human papillomaviruses, epithelial-to-mesenchymal transition and squamous pre-malignant or malignant lesions of the uterine cervix: a …

G Barillari, R Bei, V Manzari, A Modesti - International journal of molecular …, 2021 - mdpi.com
Wound healing requires static epithelial cells to gradually assume a mobile phenotype
through a multi-step process termed epithelial-to-mesenchymal transition (EMT). Although it …

[HTML][HTML] MiR-148a suppressed cell invasion and migration via targeting WNT10b and modulating β-catenin signaling in cisplatin-resistant colorectal cancer cells

L Shi, J Xi, X Xu, B Peng, B Zhang - Biomedicine & pharmacotherapy, 2019 - Elsevier
Cancer stem cells (CSCs) are suggested to be responsible for high recurrence rate and
metastasis of colorectal cancer (CRC). Identifying novel targets that can suppress CSCs …

[HTML][HTML] CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and STAT3 signalling in cervical squamous cell carcinoma

XT Mo, THY Leung, HWM Tang, MKY Siu… - British Journal of …, 2020 - nature.com
Background CD109 was involved in the tumorigenesis and progression of various cancers
via TGF-β1 signalling and STAT3 activation. As CD109 is strongly expressed in cervical …

An insight into the role of UTF1 in development, stem cells, and cancer

K Raina, C Dey, M Thool, S Sudhagar… - Stem Cell Reviews and …, 2021 - Springer
The curiosity to understand the mechanisms regulating transcription in pluripotent cells
resulted in identifying a unique transcription factor named Undifferentiated embryonic cell …

[HTML][HTML] CRKL regulates alternative splicing of cancer-related genes in cervical cancer samples and HeLa cell

Q Song, F Yi, Y Zhang, DK Jun Li, Y Wei, H Yu… - BMC cancer, 2019 - Springer
Background Aberrant spliced isoforms are specifically associated with cancer progression
and metastasis. The cytoplasmic adaptor CRKL (v-crk avian sarcoma virus CT10 oncogene …

Cervical cancer stem cells: opportunities and challenges

R Chhabra - Journal of cancer research and clinical oncology, 2015 - Springer
Introduction Cervical cancer remains a leading cause of cancer-related deaths in women in
spite of screening and vaccination programs. The current treatment strategies including …

[HTML][HTML] Doxycycline induces apoptosis and inhibits proliferation and invasion of human cervical carcinoma stem cells

B Yang, Y Lu, AI Zhang, A Zhou, L Zhang, L Zhang… - PloS one, 2015 - journals.plos.org
Background Cancer stem cells (CSCs) are proposed to be responsible for high recurrence
rate in cervical carcinoma. Reagents that can suppress the proliferation and differentiation of …

Upsetting the balance: when viruses manipulate cell polarity control

M Thomas, L Banks - Journal of molecular biology, 2018 - Elsevier
The central importance of cell polarity control is emphasized by the frequency with which it is
targeted by many diverse viruses. It is clear that in targeting key polarity control proteins …

[HTML][HTML] Role of Oct3/4 in cervical cancer tumorigenesis

SI Clemente-Periván, Y Gómez-Gómez… - Frontiers in …, 2020 - frontiersin.org
Cervical cancer (CC) is the fourth most common type of cancer that affects women.
Compared to other types of cancer, CC has a high mortality rate in women worldwide …