In the mouse telencephalon, Dlx homeobox transcription factors are essential for the
tangential migration of subpallial-derived GABAergic interneurons to neocortex. However …

ABSTRACT In Hoxa-2−/− embryos, the normal skeletal elements of the second branchial
arch are replaced by a duplicated set of first arch elements. We show here that Hoxa-2 …

Simple Summary DLX homeobox family genes encode transcription factors that have
indispensable roles in embryonic and postnatal development. These genes are critically …

The homeodomain family of transcription factors plays a fundamental role in a diverse set of
functions that include body plan specification, pattern formation and cell fate determination …

Alkaline phosphatase (ALP) is a widely accepted bone marker. Its expression is stimulated
by bone morphogenetic protein (BMP)-2 treatment, the activation of BMP receptors and R …

Majoradvances in the diagnosis and treatment of oral clefts have been made in the past 50
years, and recent genetics and epidemiological studies have led to new theories about the …

A conserved endothelin 1 signaling pathway patterns the jaw and other pharyngeal skeletal
elements in mice, chicks and zebrafish. In zebrafish, endothelin 1 (edn1 or sucker) is …

Bone formation is presumably a complex and well‐orchestrated process of osteoblast
lineage‐specific differentiation. As members of the TGFβ superfamily, bone morphogenetic …

ABSTRACT BMP signaling is essential for a wide variety of developmental processes. To
evaluate the role of Bmp2/4 in cranial neural crest (CNC) formation or differentiation after its …

Runx2 (Cbfa1) is a runt domain transcription factor that is essential for bone development
and tooth morphogenesis. Teeth form as ectodermal appendages and their development is …