Diabetic retinopathy (DR) is a leading cause for blindness among working-aged adults. The
growing prevalence of diabetes urges for cost-effective tools to improve the compliance of …

Over‐and underexposure to cholesterol activates glia in neurodegenerative brain and
retinal diseases but the molecular targets of cholesterol in glial cells are not known. Here …

Diabetic retinopathy (DR) is a devastating complication of diabetes with a prevalence rate of
35%, and no effective treatment options. Since the most visible clinical features of DR are …

CYP46A1 is the cytochrome P450 enzyme that converts cholesterol to 24-
hydroxycholesterol, a cholesterol elimination product and a potent liver X receptor (LXR) …

Background Diabetic retinopathy (DR) is the foremost cause of vision loss among the global
working-age population, and statins are among the most frequently prescribed drugs for lipid …

Diabetic retinopathy (DR) is one of the major complications of diabetic eye diseases,
causing vision loss and blindness worldwide. The concept of diabetic retinopathy has …

Vision disorders are one of the most serious complications of diabetes mellitus (DM)
affecting the quality of life of patients and eventually cause blindness. The ocular lesions in …

Chronic metabolic diseases arise from changes in metabolic fluxes through biomolecular
pathways and gene networks accumulated over the lifetime of an individual. While clinical …

Background. This study is aimed at investigating the systemic risk factors of diabetic
retinopathy and further establishing a risk prediction model for DR development in T2DM …

Diabetes mellitus has been a major cause of concern for the past few decades. As the
number of diabetic patients increases, so too does the occurrence of its complications …