Metals to combat antimicrobial resistance

A Frei, AD Verderosa, AG Elliott, J Zuegg… - Nature Reviews …, 2023 - nature.com
Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

[HTML][HTML] Global threat of carbapenem-resistant Gram-negative bacteria

SS Jean, D Harnod, PR Hsueh - Frontiers in cellular and infection …, 2022 - frontiersin.org
Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

The microbiology of bloodstream infection: 20-year trends from the SENTRY antimicrobial surveillance program

DJ Diekema, PR Hsueh, RE Mendes… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Bloodstream infection (BSI) organisms were consecutively collected from> 200 medical
centers in 45 nations between 1997 and 2016. Species identification and susceptibility …

Multidrug-resistant Acinetobacter baumannii infections in COVID-19 patients hospitalized in intensive care unit

A Russo, F Gavaruzzi, G Ceccarelli, C Borrazzo… - Infection, 2022 - Springer
Objectives Superinfections in patients hospitalized in intensive care unit (ICU) are an
important and challenging complication, also in COVID-19. However, no definitive data are …

Current treatment strategies against multidrug-resistant bacteria: A review

A Parmanik, S Das, B Kar, A Bose, GR Dwivedi… - Current …, 2022 - Springer
There are several bacteria called superbugs that are resistant to multiple antibiotics which
can be life threatening specially for critically ill and hospitalized patients. This article …

Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections

RK Shields, DL Paterson… - Clinical Infectious …, 2023 - academic.oup.com
Carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRAB) is one of
the top-priority pathogens for new antibiotic development. Unlike other antibiotic-resistant …

[HTML][HTML] Clinical data from studies involving novel antibiotics to treat multidrug-resistant Gram-negative bacterial infections

SS Kanj, M Bassetti, P Kiratisin, C Rodrigues… - International Journal of …, 2022 - Elsevier
Abstract Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to
global healthcare, worsening outcomes and increasing mortality among infected patients …

In Vitro Activity of Sulbactam-Durlobactam against Global Isolates of Acinetobacter baumannii-calcoaceticus Complex Collected from 2016 to 2021

JA Karlowsky, MA Hackel, SM McLeod… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Sulbactam-durlobactam is a β-lactam-β-lactamase inhibitor combination designed to treat
serious Acinetobacter baumannii-calcoaceticus complex (ABC) infections, including …

[HTML][HTML] Carbapenem-resistant Acinetobacter baumannii: in pursuit of an effective treatment

ET Piperaki, LS Tzouvelekis, V Miriagou… - Clinical Microbiology and …, 2019 - Elsevier
Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) has gained
global notoriety as a critically important nosocomial pathogen. It mostly affects debilitated …