Background—Infective endocarditis is a potentially lethal disease that has undergone major
changes in both host and pathogen. The epidemiology of infective endocarditis has become …

LRRC4 is a novel relatively specific gene, which displays significant down-regulation in
primary brain tumor biopsies and has the potential to suppress brain tumor growth. In this …

Potential Biases Most studies of IE are affected by selection, survival, and referral bias. They
make it difficult to study the natural history of IE in the general population, because treated …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Echocardiography plays a key role in the assessment of infective endocarditis (IE). It is
useful for the diagnosis of endocarditis, the assessment of the severity of the disease, the …

Background—Despite advances in medical, surgical, and critical care interventions, infective
endocarditis remains a disease that is associated with considerable morbidity and mortality …

Objectives: We describe the management and outcome of permanent pacemaker (PPM) and
implantable cardioverter-defibrillator (ICD) infections in a large cohort of patients seen at a …

Background—The incidence of embolic events (EE) and death is still high in patients with
infective endocarditis (IE), and data about predictors of these 2 major complications are …

The role of surgery in active IE has expanded progressively since early reports of successful
outcome. 10 Subsequent declines in mortality may be attributed to a variety of improvements …

The diagnosis of cardiac device infection and, more importantly, accurate localization of the
infection site, such as defibrillator pocket, pacemaker lead, along the peripheral driveline or …