Clostridium difficile infection

J Czepiel, M Dróżdż, H Pituch, EJ Kuijper… - European Journal of …, 2019 - Springer
Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …

Clinical application and potential of fecal microbiota transplantation

RE Ooijevaar, EM Terveer, HW Verspaget… - Annual review of …, 2019 - annualreviews.org
Fecal microbiota transplantation (FMT) is a well-established treatment for recurrent
Clostridioides difficile infection. FMT has become a more readily available and useful new …

Safety and tolerability of SER-109 as an investigational microbiome therapeutic in adults with recurrent Clostridioides difficile infection: a phase 3, open-label, single …

MD Sims, S Khanna, P Feuerstadt, TJ Louie… - JAMA Network …, 2023 - jamanetwork.com
Importance A safe and effective treatment for recurrentClostridioides difficileinfection (CDI) is
urgently needed. Antibiotics kill toxin-producing bacteria but do not repair the disrupted …

Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for …

LC McDonald, DN Gerding, S Johnson… - Clinical infectious …, 2018 - academic.oup.com
Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

[HTML][HTML] Proton pump inhibitors therapy and risk of Clostridium difficile infection: Systematic review and meta-analysis

A Trifan, C Stanciu, I Girleanu, OC Stoica… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs)
therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a …

[HTML][HTML] Recurrent Clostridium difficile infection: risk factors, treatment, and prevention

JH Song, YS Kim - Gut and liver, 2019 - ncbi.nlm.nih.gov
The most common cause of antibiotic-associated diarrhea is Clostridium difficile infection
(CDI). Recurrent C. difficile infection (rCDI) often occurs after successful treatment of CDI …

Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection in Patients at Increased Risk for Recurrence

DN Gerding, CP Kelly, G Rahav, C Lee… - Clinical infectious …, 2018 - academic.oup.com
Background Bezlotoxumab is a human monoclonal antibody against Clostridium difficile
toxin B indicated to prevent C. difficile infection (CDI) recurrence (rCDI) in adults at high risk …

2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients

M Sartelli, S Di Bella, LV McFarland, S Khanna… - World Journal of …, 2019 - Springer
In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and
severity in many countries worldwide. The increase in CDI incidence has been particularly …

Increasing Incidence of Multiply Recurrent Clostridium difficile Infection in the United States: A Cohort Study

GK Ma, CM Brensinger, Q Wu… - Annals of internal …, 2017 - acpjournals.org
Background: Clostridium difficile infection (CDI), the most common health care–associated
infection, often recurs. Fecal microbiota transplantation is increasingly used to treat multiply …

[HTML][HTML] Risk factors for Clostridium difficile infections–an overview of the evidence base and challenges in data synthesis

P Eze, E Balsells, MH Kyaw, H Nair - Journal of global health, 2017 - ncbi.nlm.nih.gov
Background Recognition of a broad spectrum of disease and development of Clostridium
difficile infection (CDI) and recurrent CDI (rCDI) in populations previously considered to be …