PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS‐STING‐Mediated Interferon Response
X Geng, C Zhang, M Li, J Wang, F Ji, H Feng… - Advanced …, 2022 - Wiley Online Library
The Plk1‐interacting checkpoint helicase (PICH) protein localizes to ultrafine anaphase
DNA bridges in mitosis along with a complex of DNA repair proteins. Previous studies show …
DNA bridges in mitosis along with a complex of DNA repair proteins. Previous studies show …
[HTML][HTML] Expanding hematopoietic stem cell ex vivo: recent advances and technical considerations
JA Rubio-Lara, KJ Igarashi, S Sood, A Johansson… - Experimental …, 2023 - Elsevier
Hematopoietic stem cells (HSCs) are the most primitive cell type in the hematopoietic
hierarchy, which are responsible for sustaining the lifelong production of mature blood and …
hierarchy, which are responsible for sustaining the lifelong production of mature blood and …
Hematopoietic stem and progenitors cells gene editing: Beyond blood disorders
V Buffa, JR Alvarez Vargas, A Galy… - Frontiers in Genome …, 2023 - frontiersin.org
Lessons learned from decades-long practice in the transplantation of hematopoietic stem
and progenitor cells (HSPCs) to treat severe inherited disorders or cancer, have set the …
and progenitor cells (HSPCs) to treat severe inherited disorders or cancer, have set the …
Enzyme‐Photodynamic Adaptive Bionic Periosteum for Bone Revitalization
Y Chen, X Jin, J Lu, S Li, C Li, C Yu… - Advanced Functional …, 2024 - Wiley Online Library
The lack of periosteum in bone allografts is considered a major cause of bone graft failure;
however, the currently used artificial periosteum has failed to proactively adapt to its …
however, the currently used artificial periosteum has failed to proactively adapt to its …
Exploring the potential of predicted miRNAs on the genes involved in the expansion of hematopoietic stem cells
M Elahimanesh, N Shokri, R Shabani, M Rahimi… - Scientific Reports, 2024 - nature.com
A major challenge in therapeutic approaches applying hematopoietic stem cells (HSCs) is
the cell quantity. The primary objective of this study was to predict the miRNAs and anti …
the cell quantity. The primary objective of this study was to predict the miRNAs and anti …
[HTML][HTML] CD49b identifies functionally and epigenetically distinct subsets of lineage-biased hematopoietic stem cells
E Somuncular, J Hauenstein, P Khalkar… - Stem Cell Reports, 2022 - cell.com
Hematopoiesis is maintained by functionally diverse lineage-biased hematopoietic stem
cells (HSCs). The functional significance of HSC heterogeneity and the regulatory …
cells (HSCs). The functional significance of HSC heterogeneity and the regulatory …
Enhanced Cellular Uptake through Nanotopography‐Induced Macropinocytosis
Efficient cellular uptake of biomolecules, including genetic material, mRNA, proteins, and
nanoparticles, requires novel approaches to overcome inherent cellular barriers. Here, the …
nanoparticles, requires novel approaches to overcome inherent cellular barriers. Here, the …
BML‐260 promotes the growth of cord blood and mobilized peripheral blood hematopoietic stem and progenitor cells with improved reconstitution ability
Hematopoietic stem cells (HSCs), which are multipotent and have the ability to self‐renew,
are frequently used in the treatment of hematological diseases and cancer. Small molecules …
are frequently used in the treatment of hematological diseases and cancer. Small molecules …
Bone marrow-derived mononuclear stem cells in the treatment of retinal degenerations
D García-Ayuso, J Di Pierdomenico… - Neural Regeneration …, 2022 - journals.lww.com
Retinal degenerative diseases affecting the outer retina in its many forms (inherited,
acquired or induced) are characterized by photoreceptor loss, and represent currently a …
acquired or induced) are characterized by photoreceptor loss, and represent currently a …
Combating bone marrow failure with polymer materials
Bone marrow failure (BMF) has become one of the most studied autoimmune disorders,
particularly due to its prevalence both as an inherited disease, but also as a result of …
particularly due to its prevalence both as an inherited disease, but also as a result of …