The nuclear envelope is tethered to the cytoskeleton. The best known attachments of all
elements of the cytoskeleton are via the so-called LINC complex. However, the nuclear pore …

The linker of nucleoskeleton and cytoskeleton (LINC) complex is composed of the inner
nuclear membrane-spanning SUN proteins and the outer nuclear membrane-spanning …

The linker of nucleoskeleton and cytoskeleton (LINC) is a conserved nuclear envelope-
spanning molecular bridge that is responsible for the mechanical integration of the nucleus …

Nemaline myopathy (NM) is a skeletal muscle disorder caused by mutations in genes that
are generally involved in muscle contraction, in particular those related to the structure …

Abstract ATR (Ataxia Telangiectasia and Rad3-related) is a member of the
Phosphatidylinositol 3-kinase-related kinases (PIKKs) family, amongst six other vertebrate …

A CTG repeat expansion in the DMPK gene is the causative mutation of myotonic dystrophy
type 1 (DM1). Transcription of the expanded CTG repeat produces toxic gain-of-function …

Lung cancer is the most common cause of cancer‑related deaths, and early diagnosis and
targeted therapy are extremely important in the treatment of this disease. Sperm‑associated …

Understanding the structure and structure–function relationships of membrane proteins is a
fundamental problem in biomedical research. Given the difficulties inherent to performing …

The LINC complex, consisting of interacting SUN and KASH proteins, mechanically couples
nuclear contents to the cytoskeleton. In meiosis, the LINC complex transmits microtubule …

The physicochemical properties and cytotoxicity of diverse gold nanoparticle (AuNP)
morphologies with smooth surfaces have been examined extensively. Much less is known …