Infertility in men: advances towards a comprehensive and integrative strategy for precision theranostics

M Assidi - Cells, 2022 - mdpi.com
Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

Estrogenic and non-estrogenic disruptor effect of zearalenone on male reproduction: a review

A Balló, K Busznyákné Székvári, P Czétány… - International journal of …, 2023 - mdpi.com
According to some estimates, at least 70% of feedstuffs and finished feeds are contaminated
with one or more mycotoxins and, due to its significant prevalence, both animals and …

A review on the impact of oxidative stress and medicinal plants on Leydig cells

E Monageng, U Offor, NB Takalani, K Mohlala… - Antioxidants, 2023 - mdpi.com
Leydig cells are essential for steroidogenesis and spermatogenesis. An imbalance in the
production of reactive oxygen species (ROS) and the cellular antioxidant level brings about …

Oxidative stress and idiopathic male infertility

P Sengupta, S Roychoudhury, M Nath… - Oxidative Stress and …, 2022 - Springer
Idiopathic male infertility (IMI) refers to the condition where semen quality declines, but exact
causatives are not identified. This occurs in almost 30–40% of infertile men. Traditional …

Phospholipases and reactive oxygen species derived lipid biomarkers in healthy and diseased humans and animals–A focus on lysophosphatidylcholine

KM Engel, J Schiller, CE Galuska, B Fuchs - Frontiers in Physiology, 2021 - frontiersin.org
Phospholipids (PL) are converted into lipid biomarkers by the action of phospholipases and
reactive oxygen species (ROS), which are activated or released under certain physiological …

[HTML][HTML] Impact of antioxidant therapy on natural pregnancy outcomes and semen parameters in infertile men: a systematic review and meta-analysis of randomized …

A Agarwal, R Cannarella, R Saleh… - The World Journal of …, 2023 - ncbi.nlm.nih.gov
Purpose Seminal oxidative stress (OS) is a recognized factor potentially associated with
male infertility, but the efficacy of antioxidant (AOX) therapy is controversial and there is no …

[HTML][HTML] Sperm DNA integrity and male infertility: a narrative review and guide for the reproductive physicians

A Farkouh, G Salvio, S Kuroda, R Saleh… - Translational …, 2022 - ncbi.nlm.nih.gov
Sperm DNA integrity and male infertility: a narrative review and guide for the reproductive
physicians - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Antioxidant Nanoparticles Restore Cisplatin-Induced Male Fertility Defects by Promoting MDC1-53bp1-Associated Non-Homologous DNA Repair Mechanism and …

YS Wei, YL Chen, WY Li, YY Yang, SJ Lin… - International Journal …, 2023 - Taylor & Francis
Introduction Cisplatin, a commonly used anticancer compound, exhibits severe off-target
organ toxicity. Due to its wide application in cancer treatment, the reduction of its damage to …

Age-related decline of male fertility: mitochondrial dysfunction and the antioxidant interventions

JJ Wang, SX Wang, Y Feng, RF Zhang, XY Li, Q Sun… - Pharmaceuticals, 2022 - mdpi.com
Mitochondria are structurally and functionally unique organelles in male gametes.
Apparently, as the only organelles remaining in mature sperm, mitochondria not only …

Redox balance in male infertility: Excellence through moderation—“Μέτρον ἄριστον”

EN Symeonidis, E Evgeni, V Palapelas, D Koumasi… - Antioxidants, 2021 - mdpi.com
Male infertility, a relatively common and multifactorial medical condition, affects
approximately 15% of couples globally. Based on WHO estimates, a staggering 190 million …