Rodent models in placental research. Implications for fetal origins of adult disease
N Aguilera, F Salas-Pérez, M Ortíz, D Álvarez… - Animal …, 2022 - SciELO Brasil
Rodent models in rats, mice, and guinea pigs have been extremely helpful to gain insight
into pregnancy physiology and pathologies-related. Moreover, they have allowed …
into pregnancy physiology and pathologies-related. Moreover, they have allowed …
The placenta's role in sexually dimorphic fetal growth strategies
JK Christians - Reproductive Sciences, 2022 - Springer
Fetal sex affects the risk of pregnancy complications and the long-term effects of prenatal
environment on health. Some have hypothesized that growth strategies differ between the …
environment on health. Some have hypothesized that growth strategies differ between the …
[HTML][HTML] Paternal preconception phthalate exposure alters sperm methylome and embryonic programming
Preconception environmental conditions have been demonstrated to shape sperm
epigenetics and subsequently offspring health and development. Our previous findings in …
epigenetics and subsequently offspring health and development. Our previous findings in …
Maternal metformin intervention during obese glucose-intolerant pregnancy affects adiposity in young adult mouse offspring in a sex-specific manner
JM Schoonejans, HL Blackmore, TJ Ashmore… - International Journal of …, 2021 - mdpi.com
Background: Metformin is commonly used to treat gestational diabetes mellitus. This study
investigated the effect of maternal metformin intervention during obese glucose-intolerant …
investigated the effect of maternal metformin intervention during obese glucose-intolerant …
Maternal but not fetoplacental health can be improved by metformin in a murine diet‐induced model of maternal obesity and glucose intolerance
A Hufnagel, DS Fernandez‐Twinn… - The Journal of …, 2022 - Wiley Online Library
Maternal obesity is a global problem that increases the risk of short‐and long‐term adverse
outcomes for mother and child, many of which are linked to gestational diabetes mellitus …
outcomes for mother and child, many of which are linked to gestational diabetes mellitus …
[HTML][HTML] Sulforaphane induced NRF2 activation in obese pregnancy attenuates developmental redox imbalance and improves early-life cardiovascular function in …
PM Psefteli, JK Morris, E Ehler, L Smith, J Bowe… - Redox Biology, 2023 - Elsevier
In adverse pregnancy a perturbed redox environment is associated with abnormal early-life
cardiovascular development and function. Previous studies have noted alterations in the …
cardiovascular development and function. Previous studies have noted alterations in the …
Examining sex differences in the human placental transcriptome during the first fetal androgen peak
AE Braun, KL Muench, BG Robinson, A Wang… - Reproductive …, 2021 - Springer
Sex differences in human placenta exist from early pregnancy to term, however, it is unclear
whether these differences are driven solely by sex chromosome complement or are subject …
whether these differences are driven solely by sex chromosome complement or are subject …
Lipid metabolism is dysregulated before, during and after pregnancy in a mouse model of gestational diabetes
S Furse, DS Fernandez-Twinn, D Chiarugi… - International Journal of …, 2021 - mdpi.com
The aim of the current study was to test the hypothesis that maternal lipid metabolism was
modulated during normal pregnancy and that these modulations are altered in gestational …
modulated during normal pregnancy and that these modulations are altered in gestational …
Obesity phenotype induced by high-fat diet leads to maternal-fetal constraint, placental inefficiency, and fetal growth restriction in mice
APV Sanches, JL de Oliveira, MS Ferreira… - The Journal of …, 2022 - Elsevier
The aim of this study was to investigate certain parameters regarding the maternal-fetal
outcomes in a diet-induced obesity model. Obese, glucose-intolerant females who were …
outcomes in a diet-induced obesity model. Obese, glucose-intolerant females who were …
[HTML][HTML] The Long-Term Effect of Maternal Obesity on the Cardiovascular Health of the Offspring–Systematic Review
O Matuszak, W Banach, B Pogorzały… - Current Problems in …, 2024 - Elsevier
Maternal obesity may affect offspring's cardiovascular health. Our literature search using
PubMed, Web of Sciences included original English research and Google Scholar articles …
PubMed, Web of Sciences included original English research and Google Scholar articles …