[HTML][HTML] Phytotherapeutic applications of alkaloids in treating breast cancer
S Rampogu, T Balasubramaniyam, JH Lee - Biomedicine & …, 2022 - Elsevier
Breast cancer is one of the major causes of mortality in women worldwide. The current
treatments available are radiation therapy (RT), surgery, endocrine (hormone) therapy (ET) …
treatments available are radiation therapy (RT), surgery, endocrine (hormone) therapy (ET) …
[HTML][HTML] Flavonoids and saponins: What have we got or missed?
Background Flavonoids and saponins are important bioactive compounds that have
attracted wide research interests. This review aims to summarise the state of the art of the …
attracted wide research interests. This review aims to summarise the state of the art of the …
A roadmap to establish a comprehensive platform for sustainable manufacturing of natural products in yeast
G Naseri - Nature Communications, 2023 - nature.com
Secondary natural products (NPs) are a rich source for drug discovery. However, the low
abundance of NPs makes their extraction from nature inefficient, while chemical synthesis is …
abundance of NPs makes their extraction from nature inefficient, while chemical synthesis is …
Extraction of bioactive compounds from Dipsacus fullonum leaves using deep eutectic solvents
In this study, deep eutectic solvent (DES) based systems were evaluated for selective
extraction and optimized for increased recovery of chlorogenic acid derivatives, flavone …
extraction and optimized for increased recovery of chlorogenic acid derivatives, flavone …
Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2-Arylethylamines via a Chemoenzymatic Approach
L Yang, J Li, Z Xu, P Yao, Q Wu, D Zhu, Y Ma - Organic Letters, 2022 - ACS Publications
While chiral fused-ring tetrahydroisoquinoline (THIQ) and tetrahydro-β-carboline (THβC)
scaffolds have attracted considerable interest due to their wide spectrum of biological …
scaffolds have attracted considerable interest due to their wide spectrum of biological …
Selective and Functional-Group-Tolerant Photoalkylation of Imines by Energy-Transfer Photocatalysis
Basic amines show broad bioactivity and remain a promising source of new medicines. The
direct photoalkylation of imines offers a promising strategy for complex amines. However …
direct photoalkylation of imines offers a promising strategy for complex amines. However …
[HTML][HTML] Antiparasitic potential of asteraceae plants: A comprehensive review on therapeutic and mechanistic aspects for biocompatible drug discovery
Background Medicinal herbs are used to cure parasitic protozoan diseases. Protozoan
parasites continue difficult to treat, but diverse extracts from both terrestrial and aquatic …
parasites continue difficult to treat, but diverse extracts from both terrestrial and aquatic …
A mini review on human serum albumin-natural alkaloids interaction and its role as drug carrier
Human serum albumin (HSA) is one of the main protein components of the circulatory
system. It's well characterized physiological role is to carry numerous ligands to their target …
system. It's well characterized physiological role is to carry numerous ligands to their target …
Molecular hybridization of alkaloids using 1, 2, 3-triazole-based click chemistry
Alkaloids found in multiple species, known as 'driver species', are more likely to be included
in early-stage drug development due to their high biodiversity compared to rare alkaloids …
in early-stage drug development due to their high biodiversity compared to rare alkaloids …
Alkaloids in future drug discovery
MJU Ferreira - Molecules, 2022 - mdpi.com
Alkaloids are nitrogen-containing compounds, biosynthesized by both marine and terrestrial
organisms, often with strong biological properties. They are among the largest classes of …
organisms, often with strong biological properties. They are among the largest classes of …