Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …

BB Aggarwal, KB Harikumar - The international journal of biochemistry & …, 2009 - Elsevier
Although safe in most cases, ancient treatments are ignored because neither their active
component nor their molecular targets are well defined. This is not the case, however, with …

Curcumin: from ancient medicine to current clinical trials

H Hatcher, R Planalp, J Cho, FM Torti… - Cellular and molecular life …, 2008 - Springer
Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric
(Curcuma longa). Curcumin has a surprisingly wide range of beneficial properties, including …

Curcumin as “Curecumin”: from kitchen to clinic

A Goel, AB Kunnumakkara, BB Aggarwal - Biochemical pharmacology, 2008 - Elsevier
Although turmeric (Curcuma longa; an Indian spice) has been described in Ayurveda, as a
treatment for inflammatory diseases and is referred by different names in different cultures …

[HTML][HTML] A review on mechanistic insight of plant derived anticancer bioactive phytocompounds and their structure activity relationship

K Mazumder, A Aktar, P Roy, B Biswas, ME Hossain… - Molecules, 2022 - mdpi.com
Cancer is a disorder that rigorously affects the human population worldwide. There is a
steady demand for new remedies to both treat and prevent this life-threatening sickness due …

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

AB Kunnumakkara, P Anand, BB Aggarwal - Cancer letters, 2008 - Elsevier
Because most cancers are caused by dysregulation of as many as 500 different genes,
agents that target multiple gene products are needed for prevention and treatment of cancer …

Curcumin: preventive and therapeutic properties in laboratory studies and clinical trials

AS Strimpakos, RA Sharma - Antioxidants & redox signaling, 2008 - liebertpub.com
Curcumin is a natural polyphenol used in ancient Asian medicine. Since the first article
referring to the use of curcumin to treat human disease was published in The Lancet in …

[HTML][HTML] Preparation of curcumin-loaded liposomes and evaluation of their skin permeation and pharmacodynamics

Y Chen, Q Wu, Z Zhang, L Yuan, X Liu, L Zhou - Molecules, 2012 - mdpi.com
This study aimed to investigate the in vitro skin permeation and in vivo antineoplastic effect
of curcumin by using liposomes as the transdermal drug-delivery system. Soybean …

Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of …

AB Kunnumakkara, S Guha, S Krishnan… - Cancer research, 2007 - AACR
Gemcitabine is currently the best treatment available for pancreatic cancer, but the disease
develops resistance to the drug over time. Agents that can either enhance the effects of …

Bioactive compounds: historical perspectives, opportunities, and challenges

BS Patil, GK Jayaprakasha… - Journal of agricultural …, 2009 - ACS Publications
Mom's conventional wisdom of eating fruits and vegetables to lead a healthy life has evolved
with scientific, fact-finding research during the past four decades due to advances in science …

Development and evaluation of self-microemulsifying liquid and pellet formulations of curcumin, and absorption studies in rats

S Setthacheewakul, S Mahattanadul… - European Journal of …, 2010 - Elsevier
This study describes the development and characterization of self-microemulsifying drug
delivery systems (SMEDDS) in liquid and pellet forms that result in improved solubility …