MRP1-dependent collateral sensitivity of multidrug-resistant cancer cells: identifying selective modulators inducing cellular glutathione depletion

D Lorendeau, L Dury, R Nasr… - Current medicinal …, 2017 - ingentaconnect.com
Cancer cells are permanently being selected for survival and proliferation. During this
process, tumor cells often co-opt basic physiological mechanisms to protect themselves from …

New structure–activity relationship studies in a series of N, N-bis (cyclohexanol) amine aryl esters as potent reversers of P-glycoprotein-mediated multidrug resistance …

F Orlandi, M Coronnello, C Bellucci, S Dei… - Bioorganic & medicinal …, 2013 - Elsevier
As a continuation of previous research on a new series of potent and efficacious P-gp-
dependent multidrug resistant (MDR) reversers with a N, N-bis (cyclohexanol) amine …

Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2)

CO Puentes, P Höcherl, M Kühnle, S Bauer… - Bioorganic & medicinal …, 2011 - Elsevier
Aiming at structural optimization of potent and selective ABCG2 inhibitors, such as UR-ME22-
1, from our laboratory, an efficient solid phase synthesis was developed to get convenient …

Twist1 对人乳腺癌细胞E-cadher in 表达及亚细胞定位的影响

张冲, 孙保存, 张丹芳, 刘芳, 董学易, 刘志勇, 车娜… - 中国肿瘤临床, 2013 - cjco.cn
Twist1对人乳腺癌细胞E-cadherin表达及亚细胞定位的影响* Page 1 中国肿瘤临床2013年第40卷
第9期Chin J Clin Oncol 2013, Vol. 40, No. 9 www.cjco.cn Twist1对人乳腺癌细胞E-cadherin表达 …

[HTML][HTML] The novel bis-benzylisoquinoline PY35 reverses P-glycoprotein-mediated multidrug resistance

Z Cao, M Wright, J Cheng, X Huang… - Oncology …, 2014 - spandidos-publications.com
Multidrug resistance (MDR) to chemotherapeutic drugs is the main cause of chemotherapy
failure in cancer treatment, and it generally results from expression of ATP-dependent efflux …

Editorial [Hot topic: Imaging of ABC Transporter Function and Expression (Guest Editors: Nicola Antonio Colabufo and Aren van Waarde)]

N Antonio Colabufo… - Current Topics in Medicinal …, 2010 - ingentaconnect.com
ABC transporters play a crucial role in several physiological barriers such as the blood-brain
barrier (BBB), bloodcerebrospinal fluid (B-CSF) barrier, and blood-testis barrier (BTB) …

[引用][C] Ras 和磷酸化ERK 信号通路参与三氧化二砷逆转耐药作用机制的研究

刘宝玲, 赵园园, 于丽, 何信佳, 张碧媛 - 中国肿瘤临床, 2013