[PDF][PDF] Quantitative streamlines tractography: methods and inter-subject normalisation

RE Smith, D Raffelt, JD Tournier, A Connelly - Aperture Neuro, 2022 - apertureneuro.org
Recent developments in semi-global tractogram optimisation algorithms have opened the
field of diffusion magnetic resonance imaging (MRI) to the possibility of performing …

Organisational and neuromodulatory underpinnings of structural-functional connectivity decoupling in patients with Parkinson's disease

A Zarkali, P McColgan, LA Leyland, AJ Lees… - Communications …, 2021 - nature.com
Parkinson's dementia is characterised by changes in perception and thought, and preceded
by visual dysfunction, making this a useful surrogate for dementia risk. Structural and …

Multi-tissue log-domain intensity and inhomogeneity normalisation for quantitative apparent fibre density

T Dhollander, R Tabbara, J Rosnarho-Tornstrand… - Proc …, 2021 - archive.ismrm.org
Multi-tissue constrained spherical deconvolution of diffusion MRI data yields white matter
fibre orientation distributions, from which a quantitative metric of apparent fibre density can …

Searching for optimal machine learning model to classify mild cognitive impairment (MCI) subtypes using multimodal MRI data

T Jitsuishi, A Yamaguchi - Scientific Reports, 2022 - nature.com
The intervention at the stage of mild cognitive impairment (MCI) is promising for preventing
Alzheimer's disease (AD). This study aims to search for the optimal machine learning (ML) …

Detecting microstructural deviations in individuals with deep diffusion MRI tractometry

M Chamberland, S Genc, CMW Tax… - Nature computational …, 2021 - nature.com
Most diffusion magnetic resonance imaging studies of disease rely on statistical
comparisons between large groups of patients and healthy participants to infer altered tissue …

[HTML][HTML] Correspondence between gene expression and neurotransmitter receptor and transporter density in the human brain

JY Hansen, RD Markello, L Tuominen, M Nørgaard… - NeuroImage, 2022 - Elsevier
Neurotransmitter receptors modulate signaling between neurons. Thus, neurotransmitter
receptors and transporters play a key role in shaping brain function. Due to the lack of …

White matter myelination during early infancy is linked to spatial gradients and myelin content at birth

M Grotheer, M Rosenke, H Wu, H Kular… - Nature …, 2022 - nature.com
Abstract Development of myelin, a fatty sheath that insulates nerve fibers, is critical for brain
function. Myelination during infancy has been studied with histology, but postmortem data …

Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease

A Pichet Binette, G Theaud, F Rheault, M Roy… - Elife, 2021 - elifesciences.org
Beta-amyloid (Aβ) and tau proteins, the pathological hallmarks of Alzheimer's disease (AD),
are believed to spread through connected regions of the brain. Combining diffusion imaging …

Whole-brain white matter abnormalities in human cocaine and heroin use disorders: association with craving, recency, and cumulative use

PO Gaudreault, SG King, P Malaker, N Alia-Klein… - Molecular …, 2023 - nature.com
Neuroimaging studies in substance use disorder have shown widespread impairments in
white matter (WM) microstructure suggesting demyelination and axonal damage. However …

Macro-and microstructural changes in cosmonauts' brains after long-duration spaceflight

S Jillings, A Van Ombergen, E Tomilovskaya… - Science …, 2020 - science.org
Long-duration spaceflight causes widespread physiological changes, although its effect on
brain structure remains poorly understood. In this work, we acquired diffusion magnetic …