Regulatory T cells (Tregs) and T helper 17 cells (Th17) are two CD4+ T cell subsets with
antagonist effects. Th17 cells promote inflammation, whereas Tregs are crucial in …

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death
worldwide, following strokes and cardiovascular diseases. Chronic lung inflammation is …

The imbalance of intestinal microbiota and inflammatory response is crucial in the
development of lung injury induced by PM2. 5. In recent years, probiotics have attracted …

Background Metrnl play an immunocytokine-like role in several diseases, which is also
known as meteorin-like because it is homologous to the neurotrophic factor meteorin …

Background IL-17 is a modulator of the inflammatory response and is implicated in lung
remodeling in both asthma and chronic obstructive pulmonary disease (COPD). Well as and …

The community of microorganisms known as gut microbiota that lives in the intestine confers
significant health benefits on its host, primarily in the form of immunological homeostasis …

Background Chronic obstructive pulmonary disease (COPD) has a high fatality rate and
poses a great threat to human health. Astragaloside IV (AS-IV) is proven to attenuate …

The dysbiosis of lung microbiota and inflammatory factors play a crucial role in the
occurrence of lipopolysaccharides (LPS)-induced lung injury. Recently, mogroside V (MGV) …

To analyze the predictive value of the Th17/Treg ratio for renal injury in sepsis patients, a
prospective observational study was conducted. Adult patients with sepsis were enrolled …

During infections, the timings of effector differentiation of pulmonary immune responses are
of paramount importance, as pathogen persistence and unsuppressed inflammation can …