Lactation is considered the final phase of the mammalian reproductive cycle, and the
mammary gland provides milk for nourishment and disease resistance to the newborn …

The production of recombinant proteins is one of the major successes of biotechnology.
Animal cells are required to synthesize proteins with the appropriate post-translational …

Lactoferrin is an iron-binding glycoprotein of the transferrin family, first isolated from milk but
also found in most exocrine secretions as well as in the secondary granules of neutrophils …

During the past two decades, there have been numerous attempts at using animals in order
to produce recombinant human proteins and monoclonal antibodies. However, it is only …

A cDNA fragment encoding human lactoferrin (hLF) linked to a plant microsomal retention
signal peptide (SEKDEL) was stably integrated into the Solanum tuberosum genome by …

Amid the explosion of fundamental knowledge generated from transgenic animal models, a
small group of scientists has been producing transgenic livestock with goals of improving …

Large-scale production of biopharmaceuticals by current bioreactor techniques is limited by
low transgenic efficiency and low expression of foreign proteins. In general, a bacterial …

Transgenic animal bioreactors can produce therapeutic proteins with high value for
pharmaceutical use. In this paper, we compared different systems capable of producing …

The first transgenic livestock species were reported in 1985. Since then microinjection of
foreign DNA into pronuclei of zygotes has been the method of choice. It is now being …

Infection of the mammary gland, in addition to causing animal distress, is a major economic
burden of the dairy industry. Staphylococcus aureus is the major contagious mastitis …