Foot-and-mouth disease virus non-structural protein 2B negatively regulates the RLR-mediated IFN-β induction

M Li, T Xin, X Gao, J Wu, X Wang, L Fang, X Sui… - Biochemical and …, 2018 - Elsevier
Foot-and-mouth disease virus (FMDV) is the causative agent of Foot-and-mouth disease
(FMD), which is an acute and highly contagious disease affecting pigs, cattle and other …

Type I interferon underlies severe disease associated with Junin virus infection in mice

BT Hickerson, EJ Sefing, KW Bailey, AJ Van Wettere… - Elife, 2020 - elifesciences.org
Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal
hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever …

Cytokine cascade and networks among MSM HIV seroconverters: implications for early immunotherapy

X Huang, X Liu, K Meyers, L Liu, B Su, P Wang, Z Li… - Scientific reports, 2016 - nature.com
The timing, intensity and duration of the cytokine cascade and reorganized interrelations in
cytokine networks are not fully understood during acute HIV-1 infection (AHI). Using …

An update on host-pathogen interplay and modulation of immune responses during Orientia tsutsugamushi infection

FE Díaz, K Abarca, AM Kalergis - Clinical microbiology reviews, 2018 - Am Soc Microbiol
The obligate intracellular bacterium Orientia tsutsugamushi is the causative agent of scrub
typhus in humans, a serious mite-borne disease present in a widespread area of endemicity …

Vaccines based on virus-like nano-particles for use against Middle East Respiratory Syndrome (MERS) coronavirus

A Hashemzadeh, A Avan, GA Ferns, M Khazaei - Vaccine, 2020 - Elsevier
Recent advances in virus-like nanoparticles against Middle East respiratory syndrome-
related coronavirus (MERS-CoV) can initiate vaccine production faster for Severe Acute …

MiR-103/miR-107 inhibits enterovirus 71 replication and facilitates type I interferon response by regulating SOCS3/STAT3 pathway

B Huang, H Chen, Y Zheng - Biotechnology Letters, 2021 - Springer
Abstract Background Enterovirus71 (EV71), the major cause of hand, foot, and-mouth
disease (HFMD), has increasingly become a public health challenge. Type I interferons …

Downregulation of miR-155-5p facilitates enterovirus 71 replication through suppression of type I IFN response by targeting FOXO3/IRF7 pathway

D Yang, X Wang, H Gao, B Chen, C Si, S Wang - Cell Cycle, 2020 - Taylor & Francis
ABSTRACT Enterovirus 71 (EV71), the major cause of hand-foot-and-mouth disease
(HFMD), has evolved diverse strategies to counter the type I interferon (IFN-I) response …

[HTML][HTML] ARID3a gene profiles are strongly associated with human interferon alpha production

ML Ratliff, J Garton, L Garman, MD Barron… - Journal of …, 2019 - Elsevier
Type I interferons (IFN) causes inflammatory responses to pathogens, and can be elevated
in autoimmune diseases such as systemic lupus erythematosus (SLE). We previously …

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling

NA de Weerd, AY Matthews, PR Pattie… - Journal of Biological …, 2017 - ASBMB
The interaction of IFN-β with its receptor IFNAR1 (interferon α/β receptor subunit 1) is vital for
host-protective anti-viral and anti-proliferative responses, but signaling via this interaction …

IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus

R Spolski, EE West, P Li, S Veenbergen, S Yung… - Elife, 2019 - elifesciences.org
Methicillin-resistant Staphylococcus aureus (MRSA) is a major hospital-and community-
acquired pathogen, but the mechanisms underlying host-defense to MRSA remain poorly …