Porphyromonas gingivalis Lipopolysaccharide Induced Proliferation and Activation of Natural Killer Cells in Vivo

Y Wang, W Zhang, L Xu, JO Jin - Molecules, 2016 - mdpi.com
Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) promoted different innate
immune activation than that promoted by Escherichia coli (E. coli) LPS. In this study, we …

Type I Interferon Signaling Is Required for CpG-Oligodesoxynucleotide-Induced Control of Leishmania major, but Not for Spontaneous Cure of Subcutaneous Primary or …

U Schleicher, J Liese, N Justies, T Mischke… - Frontiers in …, 2018 - frontiersin.org
We previously showed that in mice infected with Leishmania major type I interferons (IFNs)
initiate the innate immune response to the parasite at day 1 and 2 of infection. Here, we …

Myxoma virus dsRNA binding protein M029 inhibits the type I IFN-induced antiviral state in a highly species-specific fashion

MM Rahman, G McFadden - Viruses, 2017 - mdpi.com
Myxoma virus (MYXV) is a Leporipoxvirus that possesses a specific rabbit-restricted host
tropism but exhibits a much broader cellular host range in cultured cells. MYXV is able to …

Chronic exposure to arsenite enhances influenza virus infection in cultured cells

EA Amouzougan, R Lira Jr… - Journal of Applied …, 2020 - Wiley Online Library
Arsenic is a ubiquitous environmental toxicant that has been associated with human
respiratory diseases. In humans, arsenic exposure has been associated with increased risk …

Viral protein R of HIV type‐1 induces retrotransposition and upregulates glutamate synthesis by the signal transducer and activator of transcription 1 signaling …

A Doi, K Iijima, S Kano… - Microbiology and …, 2015 - Wiley Online Library
Viral protein R (Vpr) of HIV‐1 plays an important role in viral replication in macrophages.
Various lines of evidence suggest that expression of Vpr in macrophages causes …

ASK family in infection and inflammatory disease

T Okazaki - Advances in biological regulation, 2017 - Elsevier
Living organisms are continuously exposed to pathogens such as viruses and bacteria.
Soon after a limited number of germline-encoded receptors, called pathogen recognition …

慢性乙型肝炎信号转导及转录激活因子3, 5 与Treg/Th17 平衡的关系.

李敏癑, 杨红菊, 李静, 宋瑞… - Journal of Clinical …, 2022 - search.ebscohost.com
慢性乙型肝炎持续感染的免疫机制与T 淋巴细胞密切相关, T 淋巴细胞的发育需要多种细胞因子
的协调作用, 而信号转导及转录激活因子家族蛋白主要参与细胞因子的信号转导 …

IFNA1 and IFNA13 Genes Confer Genetic Predisposition to Ankylosing Spondylitis-Associated Uveitis in a Chinese Population

J Liu, H Li, T Lan, W Wang - Current Eye Research, 2021 - Taylor & Francis
Objectives Uveitis is considered the most frequent extra-articular manifestation of Ankylosing
Spondylitis (AS). Genetic factors play an important role in the pathogenesis of AS with …

[引用][C] Discovery of cancer vulnerabilities in gene expression regulation pathway

C Zhou - 2023

Cryptosporidium Uses Its CSPV1 Virus to Activate Host Type I IFN Response and Attenuate IFN-Gamma-Mediated Epithelial Anti-Parasitic Defense

S Deng - 2023 - search.proquest.com
Cryptosporidium, an apicomplexan protozoan parasite that infects the gastrointestinal
epithelium, is a leading cause of infectious diarrhea and diarrheal-related death in young …