Since the completion of the Human Genome Project in 2003, scientists have had a map of
all the base pairs that make up human DNA. Beginning in 2008, RNA-seq was developed …

“To be, or not to be? That is the question.” William Shakespeare, The Tragedy of Hamlet,
Prince of Denmark (1599-1602). Viral infection triggers host defense mechanisms that …

Plasmodium falciparum infection is one of the major health problems worldwide. The role of
host genetic factors is evidenced in malaria. Dysregulated inflammatory response to …

Mycobacterium abscessus complex (MAB) is a rapidly growing Mycobacterium (RGM),
whose clinical significance as an emerging human pathogen has been increasing …

HIV-infected persons are at particularly high risk of tuberculosis (TB) disease, especially in
TB endemic countries where M. tuberculosis transmission is common. Although antiretroviral …

The interaction of IFN-β with its receptor IFNAR1 is vital for host-protective anti-viral and anti-
proliferative responses, but signaling via this interaction can be detrimental if dysregulated …

Background: the effectiveness of the current vaccine against tuberculosis is useful to
counteract the lung forms of the disease. Its reactivation is variable or hardly efficient, which …

The protozoan parasite Trypanosoma cruzi, which causes Chagas disease, is capable of
infecting and replicating within metabolically distinct tissues such as the heart, skeletal …

Tuberculosis causes∼ 1.5 million deaths every year, thus remaining a leading cause of
death from infectious diseases in the world. A growing body of evidence demonstrates that …