Nanobiotechnology in neurodegenerative diseases
J Jampílek, K Kráľová, P Novák, M Novák - Nanobiotechnology in …, 2019 - Springer
Abstract “Neurodegenerative disease” is a term for a variety of disorders that primarily affect
neurons in the human brain and spinal cord. These diseases are presently incurable and …
neurons in the human brain and spinal cord. These diseases are presently incurable and …
Targeted drug delivery across the blood brain barrier in Alzheimer's disease
S Rocha - Current pharmaceutical design, 2013 - ingentaconnect.com
The discovery of drugs for Alzheimer's disease (AD) therapy that can also permeate the
blood brain barrier (BBB) is very difficult owing to its specificity and restrictive nature. The …
blood brain barrier (BBB) is very difficult owing to its specificity and restrictive nature. The …
Development and optimization of hydroxyapatite-ofloxacin implants for possible bone delivery in osteomyelitis treatment
A Kumar Nayak, M Saquib Hasnain… - Current drug …, 2013 - ingentaconnect.com
The present study deals with preparation, optimization and in-vitro drug release study of
hydroxyapatite (HAp)-ofloxacin for bone-implantable delivery in osteomyelitis treatment. The …
hydroxyapatite (HAp)-ofloxacin for bone-implantable delivery in osteomyelitis treatment. The …
Polymeric nanoparticles as oral delivery systems for encapsulation and release of polyphenolic compounds: Impact on quercetin antioxidant activity & bioaccessibility
H Pool, D Quintanar, JD Figueroa, JE H. Bechara… - Food Biophysics, 2012 - Springer
A delivery system containing polymeric (Eudragit) nanoparticles has been developed for
encapsulation and controlled release of bioactive flavonoids (quercetin). Nanoparticles were …
encapsulation and controlled release of bioactive flavonoids (quercetin). Nanoparticles were …
Taguchi design for optimization and development of antibacterial drug-loaded PLGA nanoparticles
H Chaudhary, V Kumar - International Journal of Biological …, 2014 - Elsevier
This research report was to develop Cefixime loaded polylactide-co-glycolide (PLGA)
nanoparticles using modified precipitation method. TEM analysis indicated formation of well …
nanoparticles using modified precipitation method. TEM analysis indicated formation of well …
Nanotherapeutics for Alzheimer's disease (AD): past, present and future
M Fazil, Shadab, S Baboota, JK Sahni… - Journal of drug …, 2012 - Taylor & Francis
Drug delivery to the brain still remains highly challenging for the treatment of Alzheimer's
disease (AD). The development of new practical treatment modalities for the treatment of AD …
disease (AD). The development of new practical treatment modalities for the treatment of AD …
Polybutylcyanoacrylate nanocarriers as promising targeted drug delivery systems
S Gao, Y Xu, S Asghar, M Chen, L Zou… - Journal of Drug …, 2015 - Taylor & Francis
Among the materials for preparing the polymeric nanocarriers, poly (n-butylcyanoacrylate)(
PBCA), a polymer with medium length alkyl side chain, is of lower toxicity and proper …
PBCA), a polymer with medium length alkyl side chain, is of lower toxicity and proper …
Effect of physicochemical properties of biodegradable polymers on nano drug delivery
Sonam, H Chaudhary, V Arora, K Kholi… - Polymer Reviews, 2013 - Taylor & Francis
This review article is to explore the utilization of biodegradable polymers and their
associated physicochemical properties in nano drug delivery (NDD). The main hub of the …
associated physicochemical properties in nano drug delivery (NDD). The main hub of the …
Development and evaluation of metronidazole loaded microsponge based gel for superficial surgical wound infections
The purpose of this study was to optimize, characterize and develop microsponge drug
delivery system for topical delivery. Antibacterial compound, metronidazole was selected as …
delivery system for topical delivery. Antibacterial compound, metronidazole was selected as …
An alternative approach for improved entrapment efficiency of hydrophilic drug substance in PLGA nanoparticles by interfacial polymer deposition following solvent …
Background: Alzheimer's disease (AD) is an age-related and irreversible neurological
disorder. The low efficacy of current therapeutic strategies is related to both poor drug …
disorder. The low efficacy of current therapeutic strategies is related to both poor drug …